Transcription Factor

Accessions: T133912_1.02 (CISBP 1.02)
Names: RORB, T133912_1.02;
Organisms: Tetraodon nigroviridis
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:PBM, family:Nuclear receptor
Length: 471
Pfam Domains: 9-77 Zinc finger, C4 type (two domains)
255-438 Ligand-binding domain of nuclear hormone receptor
Sequence:
(in bold interface residues)
1 LAAQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYSCPRQRNCLIDRTNRN 60
61 RCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLYAEVQKHQARLQEQRQQQTGEAEALAR 120
121 VYSSSLTNGLSTLNHEIGGTYANGHIIELPKGGHGNGGAVPGGYYGMDSTQPSPDQSGLD 180
181 MSGMKHIKQEPVYDLTPVPNLFSYGGYQDAQLGHSNASMGELDRLAQNIIKSHLETCQYT 240
241 TEELQQLVWQTHSYEELKVYQSKPRDVLWQQCAIQITHAIQYVVEFAKRISGFMELCQND 300
301 QILLLKSGCLEVVLVRMCRAFNPLNNTVLFEGKYGGMQMFKTLGCDELVSAVFDFAKSLC 360
361 SLQLTEEEIALFSAAVLISTDRPWLMEPRKVQKLQEKIYFALQHIMQKNHMDEDTLAKLI 420
421 SRIPTLSALCTLHTEELQAFQQLHPETVSVLFPPLYKELFNPDPNSTMGMP
Interface Residues: 18, 19, 21, 22, 28, 29, 31, 32, 35, 36, 60, 82, 84
3D-footprint Homologues: 6fbq_A, 7wnh_D, 6l6q_B, 3g9m_B, 1a6y_A, 1lo1_A, 4oln_B, 8hbm_B, 5krb_G, 2han_B, 1kb2_B, 2a66_A, 2nll_B, 1lat_A, 7xv6_B, 2ff0_A, 1dsz_A, 4umm_E, 3cbb_A, 8cef_H, 4iqr_B, 2han_A, 1hcq_E, 5cbz_E, 4tnt_B, 5e69_A, 4hn5_B, 5emc_A, 7prw_B, 5cbx_B, 3g6t_A, 1r4i_A
Binding Motifs: M1458_1.02 mbTGACCTCd
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.