Transcription Factor

Accessions: Q52M93 (JASPAR 2024)
Names: Z585B_HUMAN, zinc finger protein 41-like protein, Zinc finger protein 585B
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q52M93
Length: 769
Pfam Domains: 27-67 KRAB box
146-168 Zinc-finger double domain
158-182 C2H2-type zinc finger
176-195 Zinc-finger double domain
185-199 C2H2-type zinc finger
186-208 Zinc finger, C2H2 type
186-206 C2H2-type zinc finger
201-223 Zinc-finger double domain
213-225 C2H2-type zinc finger
214-236 Zinc finger, C2H2 type
214-236 C2H2-type zinc finger
228-253 Zinc-finger double domain
242-264 Zinc finger, C2H2 type
242-264 C2H2-type zinc finger
242-251 C2H2-type zinc finger
257-279 Zinc-finger double domain
287-307 Zinc-finger double domain
297-320 C2H2-type zinc finger
298-320 Zinc finger, C2H2 type
298-320 C2H2-type zinc finger
313-337 Zinc-finger double domain
355-374 C2H2-type zinc finger
355-376 C2H2-type zinc finger
356-376 Zinc finger, C2H2 type
371-393 Zinc-finger double domain
381-402 C2H2-type zinc finger
382-404 Zinc finger, C2H2 type
382-404 C2H2-type zinc finger
396-419 Zinc-finger double domain
410-432 Zinc finger, C2H2 type
410-432 C2H2-type zinc finger
425-449 Zinc-finger double domain
437-458 C2H2-type zinc finger
438-460 C2H2-type zinc finger
438-460 Zinc finger, C2H2 type
456-477 Zinc-finger double domain
466-488 Zinc finger, C2H2 type
466-488 C2H2-type zinc finger
466-488 C2H2-type zinc finger
480-505 Zinc-finger double domain
494-516 Zinc finger, C2H2 type
494-516 C2H2-type zinc finger
494-514 C2H2-type zinc finger
509-533 Zinc-finger double domain
521-532 C2H2-type zinc finger
522-544 Zinc finger, C2H2 type
522-544 C2H2-type zinc finger
536-560 Zinc-finger double domain
550-572 Zinc finger, C2H2 type
550-570 C2H2-type zinc finger
567-587 Zinc-finger double domain
578-600 C2H2-type zinc finger
578-600 Zinc finger, C2H2 type
578-598 C2H2-type zinc finger
595-617 Zinc-finger double domain
605-624 C2H2-type zinc finger
606-625 C2H2-type zinc finger
606-625 Zinc finger, C2H2 type
623-644 Zinc-finger double domain
634-656 C2H2-type zinc finger
634-656 C2H2-type zinc finger
634-656 Zinc finger, C2H2 type
648-672 Zinc-finger double domain
662-680 C2H2-type zinc finger
662-682 C2H2-type zinc finger
662-684 Zinc finger, C2H2 type
679-700 Zinc-finger double domain
689-708 C2H2-type zinc finger
690-712 C2H2-type zinc finger
690-712 Zinc finger, C2H2 type
705-729 Zinc-finger double domain
718-740 C2H2-type zinc finger
718-740 Zinc finger, C2H2 type
718-740 C2H2-type zinc finger
732-756 Zinc-finger double domain
745-756 C2H2-type zinc finger
746-768 C2H2-type zinc finger
746-768 Zinc finger, C2H2 type
Sequence:
(in bold interface residues)
1 MPASWTSPQKSSALAPEDHGSSYEGSVSFRDVAIDFSREEWRHLDLSQRNLYRDVMLETY 60
61 SHLLSVGYQVPKPEVVMLEQGKEPWALQGERPRHSCPGEKLWDHNQHRKIIGYKPASSQD 120
121 QKIYSGEKSYECAEFGKSFTWKSQFKVHLKVPTGEKLYVCIECGRAFVQKPEFITHQKTH 180
181 MREKPYKCNECGKSFFQVSSLFRHHRIHTGEKLYECSECGKGFPYNSDLSIHEKIHTGER 240
241 HHECTDCGKAFTQKSTLKIHQKIHTGERSYICIECGQAFIQKTQLIAHRRIHSGEKPYEC 300
301 NNCGKSFISKSQLQVHQRVHTRVKPYICTEYGKVFSNNSNLITHEKIQSREKSSICTECG 360
361 KAFTYRSELIIHQRIHTGEKPYECSDCGRAFTQKSALTVHQRIHTGEKSYICMKCGLAFI 420
421 RKAHLITHQIIHTGEKPYKCGHCGKLFTSKSQLHVHKRIHTGEKPYVCNKCGKAFTNRSN 480
481 LITHQKTHTGEKSYICSKCGKAFTQRSDLITHQRIHTGEKPYECNTCGKAFTQKSNLNIH 540
541 QKIHTGERQYECHECGKAFNQKSILIVHQKIHTGEKPYVCTECGRAFIRKSNFITHQRIH 600
601 TGEKPYECSDCGKSFTSKSQLLVHQPVHTGEKPYVCAECGKAFSGRSNLSKHQKTHTGEK 660
661 PYICSECGKTFRQKSELITHHRIHTGEKPYECSDCGKSFTKKSQLQVHQRIHTGEKPYVC 720
721 AECGKAFSNRSNLNKHQTTHTGDKPYKCGICGKGFVQKSVFSVHQSSHA
Interface Residues: 199, 200, 202, 203, 225, 227, 228, 253, 254, 255, 256, 399, 410, 421, 422, 423, 424, 427, 448, 449, 451, 452, 455, 476, 477, 478, 479, 480, 483, 487, 505, 506, 507, 508, 511, 515, 533, 534, 535, 536, 539, 561, 563, 564, 567, 588, 589, 591, 592, 595, 617, 618, 619, 620, 623, 645, 646, 647, 648, 650, 651, 657, 671, 672, 673, 674, 675, 676, 678, 679, 681, 682, 683, 685, 700, 701, 702, 703, 704, 707, 728, 729, 730, 731, 732, 735, 756, 757, 758, 759, 760, 763
3D-footprint Homologues: 2lt7_A, 1ubd_C, 2kmk_A, 7w1m_H, 7y3m_I, 6e94_A, 8ssu_A, 8gn3_A, 5v3j_F, 8ssq_A, 6u9q_A, 2drp_D, 2gli_A, 1tf6_A, 7ysf_A, 7n5w_A, 7txc_E, 8h9h_G, 2jpa_A, 7y3l_A, 1tf3_A, 8cuc_F
Binding Motifs: UN0207.1 AGGAmAAAATGkTtty
UN0207.2 AGGAmAAAATGkTtt
Binding Sites: UN0207.1.1 / UN0207.1.17
UN0207.1.10
UN0207.1.11
UN0207.1.12 / UN0207.1.6
UN0207.1.13 / UN0207.1.7
UN0207.1.14 / UN0207.1.8
UN0207.1.15
UN0207.1.16 / UN0207.1.9
UN0207.1.18
UN0207.1.19
UN0207.1.2
UN0207.1.10 / UN0207.1.20
UN0207.1.1 / UN0207.1.3
UN0207.1.4
UN0207.1.2 / UN0207.1.5
UN0207.1.3 / UN0207.1.6
UN0207.1.7
UN0207.1.4 / UN0207.1.8
UN0207.1.5 / UN0207.1.9
UN0207.1.11
UN0207.1.12
UN0207.1.13
UN0207.1.14
UN0207.1.15
UN0207.1.16
UN0207.1.17
UN0207.1.18
UN0207.1.19
UN0207.1.20
UN0207.2.1 / UN0207.2.11 / UN0207.2.14 / UN0207.2.15 / UN0207.2.17 / UN0207.2.2 / UN0207.2.20 / UN0207.2.4 / UN0207.2.5 / UN0207.2.8 / UN0207.2.9
UN0207.2.10
UN0207.2.12
UN0207.2.13
UN0207.2.16 / UN0207.2.6
UN0207.2.18
UN0207.2.19
UN0207.2.3
UN0207.2.7
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.