Transcription Factor

						

			
Accessions: Q4H2S3 (JASPAR 2024)

			
Names: Q4H2S3_CIOIN
Organisms: Ciona intestinalis
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q4H2S3
Length: 414
Pfam Domains:    95-156 Domain of unknown function (DUF1898)
   96-164 HMG (high mobility group) box
  165-212 SOX transcription factor
Sequence: 
(in bold interface residues)		   1 MLTVDHNPNWMQIPYPTSGVPVIPSNAHLPPPAPIAGSTPTSGSQGDVKPYIGENGHLGG   60
  61 SMTHLSPPMMNHVQGSHNQNNNNSSANNKVPQEQRVKRPMNAFMVWSRGQRRKMAQDNPK  120
 121 MHNSEISKRLGAEWKTLSDSDKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKAILKKENK  180
 181 FGMGPGGIMGGGAGPQMSASGQRSHMSAAPIDYSQYYQHSMMAGSQDPMAYGAPSPHAYP  240
 241 AMANSGTAANRYDMYYPSYSTPTTLPSMSSLTSQHNSYAQSAYSVGGSPAYSVAQAHTPT  300
 301 NSLHSMAGSHHGSSGVHSPANTSPGASSVTSAAASSGGSPLHQQLQSMLPLHSHQLPISQ  360
 361 MYLPISEQQPASATTPTDPSHSPGLSRLNSIGPGTHYPISTSMGQLPMHMPAHM
Interface Residues: 98, 101, 103, 104, 105, 107, 111, 122, 123, 124, 127, 165, 169
3D-footprint Homologues: 6jrp_D, 2lef_A, 3u2b_C, 1o4x_B, 7m5w_A, 3f27_D, 4s2q_D, 1qrv_A, 3tmm_A, 4y60_C, 2gzk_A, 1j5n_A, 1ckt_A, 1hry_A, 3tq6_B, 7zie_A
Binding Motifs: MA1915.1 mmAwtdwcATTGTtwttkkw
MA1915.2 AwtdwcATTGT
			
Publications: Chen WC, Pauls S, Bacha J, Elgar G, Loose M, Shimeld SM. Dissection of a Ciona regulatory element reveals complexity of cross-species enhancer activity. Dev Biol 390:261-72 (2014). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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