Transcription Factor
| Accessions: | Q7KHK4 (JASPAR 2024) |
| Names: | Comb gap, Combgap, isoform A, Combgap, isoform D, LD05357p, Q7KHK4_DROME |
| Organisms: | Drosophila melanogaster |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q7KHK4 |
| Length: | 671 |
| Pfam Domains: | 179-201 C2H2-type zinc finger 179-188 C2H2-type zinc finger 179-201 Zinc finger, C2H2 type 193-218 Zinc-finger double domain 206-217 C2H2-type zinc finger 207-229 C2H2-type zinc finger 222-245 Zinc-finger double domain 235-257 C2H2-type zinc finger 235-244 C2H2-type zinc finger 235-257 Zinc finger, C2H2 type 249-272 Zinc-finger double domain 263-285 Zinc finger, C2H2 type 277-301 Zinc-finger double domain 291-313 Zinc finger, C2H2 type 291-311 C2H2-type zinc finger 291-313 C2H2-type zinc finger 319-341 Zinc finger, C2H2 type 319-329 C2H2-type zinc finger 346-369 Zinc finger, C2H2 type 346-369 C2H2-type zinc finger 346-355 C2H2-type zinc finger 361-386 Zinc-finger double domain 375-398 C2H2-type zinc finger 460-482 Zinc finger, C2H2 type 460-482 C2H2-type zinc finger 460-478 C2H2-type zinc finger 639-658 C2H2-type zinc finger |
| Sequence: (in bold interface residues) | 1 MCAAQNPPPFGYTWGFADNGNRAAESVLEISPNINYTVSGESMPYLLSTDGSLAVQKDVK 60 61 GLTAGGKNNVVRRMFVVNDPSFPPGTQRVITAGGASTVVKKQDNNQQVLSLDKNCDILPG 120 121 ISVQVQKVIQGLEDNEDSQGEAPNLKLEPGTLELSPKTELQESMHFSETDATIKKERPYS 180 181 CDECGKSFLLKHHLTTHARVHTGERPHICTHCGKSFAHKHCLNTHLLLHSTERPYQCQEC 240 241 KKSFTLKHHLLTHSRVHSRERPFVCQECGRAFPLKRHLVTHSKFHAGERPYVCEECGESF 300 301 AQENHLIMHSRFHGSLNPFVCAECGASFPRKFQLVNHGRIHGKIPHSCTVCGKEFLQKRT 360 361 LVSHMRRVHTGEQAHPCVSCGEGFLTKAELHQHVRTAHNGVNPNTSSATIIANQQLQQAH 420 421 HHQAGQQTHPQTITVVSNPGNSTLLTVSTTDANGVARPQFVCRECGSAFNSREALALHLR 480 481 LHTGDKSLMTDLCALTAALPGHFLSTASLNPGTVVTANPNLVGQSPVPVQIISSTGQVMS 540 541 QTTLVQAANSTHPQAVVTAVPTMPVHGQQQHLQHVAQQQQQQQQQQQQQQQHVVSVAPAN 600 601 KPKSHFCASCGKGFAAKHGLMQHNRRHPNGGCTVRTHVCECGKAFFQKNHLMLHQRQHLE 660 661 TKPAISQQQVC |
| Interface Residues: | 168, 170, 171, 189, 190, 191, 192, 193, 195, 196, 197, 198, 199, 200, 202, 217, 218, 219, 220, 221, 222, 223, 224, 225, 245, 246, 247, 248, 249, 251, 252, 256, 271, 272, 273, 274, 275, 276, 277, 279, 280, 283, 284, 301, 302, 303, 304, 305, 306, 307, 308, 329, 330, 331, 332, 333, 334, 336, 356, 357, 358, 359, 360, 361, 363, 366, 386, 388, 389, 392, 398, 412, 414, 416, 417, 420, 424, 441, 442, 443, 444, 471 |
| 3D-footprint Homologues: | 2i13_A, 3uk3_C, 8cuc_F, 1g2f_F, 6wmi_A, 8ssq_A, 7w1m_H, 5und_A, 8ssu_A, 1mey_C, 5v3j_F, 2gli_A, 1f2i_J, 4m9v_C, 1ubd_C, 2jpa_A, 1tf3_A, 2wbs_A, 1tf6_A, 2kmk_A, 6ml4_A, 8gn3_A, 5yel_A, 6e94_A, 7eyi_G, 6jnm_A, 7y3l_A, 5kl3_A, 5ei9_F, 1llm_D, 4x9j_A, 2lt7_A, 6a57_A, 8h9h_G, 5k5i_A, 7n5w_A, 6blw_A, 5kkq_D, 6u9q_A, 7ysf_A, 7y3m_I, 7txc_E, 5yj3_D |
| Binding Motifs: | MA2107.1 / UN0437.1 ACACACACAcA |
| Binding Sites: | MA2107.1.1 / UN0437.1.1 MA2107.1.10 / UN0437.1.10 MA2107.1.11 / UN0437.1.11 MA2107.1.12 / UN0437.1.12 MA2107.1.13 / UN0437.1.13 MA2107.1.14 / UN0437.1.14 MA2107.1.15 / UN0437.1.15 MA2107.1.16 / UN0437.1.16 MA2107.1.17 / UN0437.1.17 MA2107.1.18 / UN0437.1.18 MA2107.1.19 / UN0437.1.19 MA2107.1.2 / UN0437.1.2 MA2107.1.20 / UN0437.1.20 MA2107.1.3 / UN0437.1.3 MA2107.1.4 / UN0437.1.4 MA2107.1.5 / UN0437.1.5 MA2107.1.6 / UN0437.1.6 MA2107.1.7 / UN0437.1.7 MA2107.1.8 / UN0437.1.8 MA2107.1.9 / UN0437.1.9 |
| Publications: | Chetverina D, Vorobyeva NE, Mazina MY, Fab LV, Lomaev D, Golovnina A, Mogila V, Georgiev P, Ziganshin RH, Erokhin M. Comparative interactome analysis of the PRE DNA-binding factors: purification of the Combgap-, Zeste-, Psq-, and Adf1-associated proteins. Cell Mol Life Sci 79:353 (2022). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.