Transcription Factor

Accessions: O80542 (JASPAR 2024), T01956 (AthalianaCistrome v4_May2016)
Names: ERF19_ARATH, At1g22810, T01956;
Organisms: Arabidopsis thaliana
Libraries: JASPAR 2024 1, AthalianaCistrome v4_May2016 2
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
2 O'Malley RC, Huang SS, Song L, Lewsey MG, Bartlett A, Nery JR, Galli M, Gallavotti A, Ecker JR. Cistrome and Epicistrome Features Shape the Regulatory DNA Landscape. Cell 165:1280-92 (2016). [Pubmed]
Notes: ecotype:Col-0, experiment type: ampDAP-seq, experiment type: ampDAP-seq (methyl-cytosines removed by PCR), experiment type: DAP-seq, family:AP2-EREBP
Length: 144
Pfam Domains: 12-62 AP2 domain
Sequence:
(in bold interface residues)
1 MDYRESTGESQSKYKGIRRRKWGKWVSEIRVPGTRDRLWLGSFSTAEGAAVAHDVAFFCL 60
61 HQPDSLESLNFPHLLNPSLVSRTSPRSIQQAASNAGMAIDAGIVHSTSVNSGCGDTTTYY 120
121 ENGADQVEPLNISVYDYLGGHDHV
Interface Residues: 18, 20, 22, 23, 24, 28, 30, 37, 39
3D-footprint Homologues: 5wx9_A, 7wq5_A, 1gcc_A, 5i44_I
Binding Motifs: M0062 / MA1255.1 GgyggyGgCGGTGGh
M0056 cdyCACCGACAmhrm
MA1424.1 cdyCACCGACAmhrm
MA1424.2 yCACCGACA
Binding Sites: MA1255.1.6
MA1255.1.8
MA1255.1.4
MA1255.1.15
MA1255.1.1
MA1255.1.10
MA1255.1.11
MA1255.1.12 / MA1255.1.7
MA1255.1.13
MA1255.1.14
MA1255.1.16
MA1255.1.17
MA1255.1.18
MA1255.1.19
MA1255.1.2
MA1255.1.20
MA1255.1.3
MA1255.1.5
MA1255.1.9
Publications: Magnani E, Sjölander K, Hake S. From endonucleases to transcription factors: evolution of the AP2 DNA binding domain in plants. Plant Cell 16:2265-77 (2004). [Pubmed]

Lambert SA, Yang AWH, Sasse A, Cowley G, Albu M, Caddick MX, Morris QD, Weirauch MT, Hughes TR. Similarity regression predicts evolution of transcription factor sequence specificity. Nat Genet 51:981-989 (2019). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.