Transcription Factor
| Accessions: | T015234_1.02 (CISBP 1.02), P28574 (JASPAR 2024) |
| Names: | Max, T015234_1.02;, MAX_MOUSE, Myc-associated factor X, Myc-binding novel HLH/LZ protein, Protein max, Protein myn |
| Organisms: | Mus musculus |
| Libraries: | CISBP 1.02 1, JASPAR 2024 2 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Notes: | experiment type:PBM, family:bHLH |
| Length: | 160 |
| Pfam Domains: | 24-74 Helix-loop-helix DNA-binding domain |
| Sequence: (in bold interface residues) | 1 MSDNDDIEVESDEEQPRFQSAADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASR 60 61 AQILDKATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQVRALEKARSSAQLQTNYPSSDN 120 121 SLYTNAKGGTISAFDGGSDSSSESEPEEPQSRKKLRMEAS |
| Interface Residues: | 25, 27, 28, 29, 31, 32, 35, 36, 40, 60 |
| 3D-footprint Homologues: | 8osb_B, 7z5k_B, 1a0a_B, 1an4_A, 7f2f_B, 5eyo_A, 7xq5_A, 5v0l_A, 1am9_A, 7rcu_E, 5gnj_I, 6g1l_A, 8osl_O, 7ssa_L, 5i50_B, 8hov_A, 7d8t_A, 4h10_A, 7xi3_A, 5nj8_D, 8ia3_B |
| Binding Motifs: | PB0147.1 ktGyCAyGcGaCdk M0221_1.02 sCrCrTGsy PB0043.1 kgmsCACGTGgkcrkk |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] |
| Related annotations: | PaperBLAST |
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