Transcription Factor

						

			
Accessions: REST_MOUSE (HOCOMOCO 10)

			
Names: Neural-restrictive silencer factor, RE1-silencing transcription factor, REST_MOUSE
Organisms: Mus musculus
Libraries: HOCOMOCO 10 1
1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed]
Uniprot: Q8VIG1
Length: 1082
Pfam Domains:   212-233 C2H2-type zinc finger
  258-279 Zinc-finger double domain
  271-293 C2H2-type zinc-finger domain
  285-309 Zinc-finger double domain
  299-321 C2H2-type zinc finger
  299-321 Zinc finger, C2H2 type
  299-322 C2H2-type zinc-finger domain
  313-338 Zinc-finger double domain
  327-350 C2H2-type zinc finger
  327-351 C2H2-type zinc-finger domain
  343-365 Zinc-finger double domain
  357-378 C2H2-type zinc-finger domain
  370-394 Zinc-finger double domain
Sequence: 
(in bold interface residues)		   1 MATQVMGQSSGGGSLFNNSANMGMALTNDMYDLHELSKAELAAPQLIMLANVALTGEASG   60
  61 SCCDYLVGEERQMAELMPVGDNHFSESEGEGLEESADLKGLENMELGSLELSAVEPQPVF  120
 121 EASAAPEIYSANKDPAPETPVAEDKCRSSKAKPFRCKPCQYEAESEEQFVHHIRIHSAKK  180
 181 FFVEESAEKQAKAWESGSSPAEEGEFSKGPIRCDRCGYNTNRYDHYMAHLKHHLRAGENE  240
 241 RIYKCIICTYTTVSEYHWRKHLRNHFPRKVYTCSKCNYFSDRKNNYVQHVRTHTGERPYK  300
 301 CELCPYSSSQKTHLTRHMRTHSGEKPFKCDQCNYVASNQHEVTRHARQVHNGPKPLNCPH  360
 361 CDYKTADRSNFKKHVELHVNPRQFNCPVCDYAASKKCNLQYHFKSKHPTCPSKTMDVSKV  420
 421 KLKKTKKREADLLNNAVSNEKMENEQTKTKGDVSGKKNEKPVKAVGKDASKEKKPGSSVS  480
 481 VVQVTTRTRKSAVAAETKAAEVKHTDGQTGNNPEKPCKAKKNKRKKDAEAHPSEEPVNEG  540
 541 PVTKKKKKSECKSKIGTNVPKGGGRAEERPGVKKQSASLKKGTKKTPPKTKTSKKGGKLA  600
 601 PKGMGQTEPSSGALAQVGVSPDPALIQAEVTGSGSSQTELPSPMDIAKSEPAQMEVSLTG  660
 661 PPPVEPAQMEPSPAKPPQVEAPTYPQPPQRGPAPPTGPAPPTGPAPPTEPAPPTGLAEME  720
 721 PSPTEPSQKEPPPSMEPPCPEELPQAEPPPMEDCQKELPSPVEPAQIEVAQTAPTQVQEE  780
 781 PPPVSEPPRVKPTKRSSLRKDRAEKELSLLSEMARQEQVLMGVGLVPVRDSKLLKGNKSA  840
 841 QDPPAPPSPSPKGNSREETPKDQEMVSDGEGTIVFPLKKGGPEEAGESPAELAALKESAR  900
 901 VSSSEQNSAMPEGGASHSKCQTGSSGLCDVDTEQKTDTVPMKDSAAEPVSPPTPTVDRDA  960
 961 GSPAVVASPPITLAENESQEIDEDEGIHSHDGSDLSDNMSEGSDDSGLHGARPTPPEATS 1020
1021 KNGKAGLAGKVTEGEFVCIFCDRSFRKEKDYSKHLNRHLVNVYFLEEAAEEQEEQEEREE 1080
1081 QE
Interface Residues: 196, 198, 199, 202, 222, 223, 224, 228, 232, 251, 252, 253, 254, 255, 256, 257, 259, 260, 271, 279, 280, 281, 282, 283, 284, 285, 286, 288, 290, 291, 292, 294, 309, 310, 311, 312, 313, 315, 316, 317, 320, 337, 338, 339, 340, 341, 342, 343, 344, 345, 348, 367, 368, 369, 370, 371, 373, 391, 393, 394, 395, 396, 397, 398, 401, 404
3D-footprint Homologues: 5v3j_F, 7w1m_H, 2drp_D, 7eyi_G, 2lt7_A, 2i13_A, 5yel_A, 2kmk_A, 6jnm_A, 1tf3_A, 8cuc_F, 7y3l_A, 6ml4_A, 5ei9_F, 1mey_C, 3uk3_C, 7ysf_A, 1f2i_J, 5und_A, 2gli_A, 1g2f_F, 4x9j_A, 6u9q_A, 8h9h_G, 1tf6_A, 7y3m_I, 6wmi_A, 6a57_A, 2jpa_A, 8ssq_A, 8ssu_A, 7n5w_A, 5kkq_D, 1ubd_C, 7txc_E, 5kl3_A, 5yj3_D, 5k5i_A, 1llm_D, 6blw_A, 2wbs_A, 4m9v_C, 6e94_A, 8gn3_A, 5k5l_F
Binding Motifs: REST_MOUSE.H10MO.A|M01321 yCaGsACCayGGACAGcdcCc
			
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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