Transcription Factor

Accessions: T049196_1.02 (CISBP 1.02)
Names: Egr2, T049196_1.02;
Organisms: Mus musculus
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:PBM, family:C2H2 ZF
Length: 412
Pfam Domains: 36-126 Domain of unknown function (DUF3446)
279-303 C2H2-type zinc finger
279-303 Zinc finger, C2H2 type
296-319 Zinc-finger double domain
309-331 C2H2-type zinc finger
309-331 Zinc finger, C2H2 type
323-347 Zinc-finger double domain
337-355 C2H2-type zinc finger
337-359 Zinc finger, C2H2 type
Sequence:
(in bold interface residues)
1 MINIDMTGEKRPLDLPYPSSFAPISAPRNQTFTYMGKFSIDPQYPGASCYPEGIINIVSA 60
61 GILQGVTPPASTTASSSVTSASPNPLATGPLGVCTMSQTQPELDHLYSPPPPPPPYSGCT 120
121 GDLYQDPSAFLSPPSTTSTSSLAYQPPPSYPSPKPAMDPGLIPMIPDYPGFFPSPCQRDP 180
181 HGAAGPDRKPFPCPLDSLRVPPPLTPLSTIRNFTLGGPGAGVTGPGASGGGEGPRLPGSG 240
241 SAAVTATPYNPHHLPLRPILRPRKYPNRPSKTPVHERPYPCPAEGCDRRFSRSDELTRHI 300
301 RIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHL 360
361 RQKERKSSAPSAPPSAQSSASGPGGSQAGGSLCGNSAIGGPLASCTSRTRTP
Interface Residues: 180, 205, 209, 245, 246, 248, 258, 261, 265, 268, 270, 271, 291, 292, 293, 294, 295, 297, 298, 317, 319, 320, 321, 322, 323, 325, 326, 327, 344, 347, 348, 349, 350, 351, 352, 353, 354, 355, 358, 381, 382, 383, 393, 396
3D-footprint Homologues: 7w1m_H, 8ssq_A, 5kkq_D, 8ssu_A, 6blw_A, 1tf6_A, 5ei9_F, 2kmk_A, 1tf3_A, 6jnm_A, 7n5w_A, 1ubd_C, 5k5i_A, 7ysf_A, 6u9q_A, 4x9j_A, 2gli_A, 1f2i_J, 5kl3_A, 2wbs_A, 2jpa_A, 1g2f_F, 6ml4_A, 5v3j_F, 8h9h_G, 6e94_A, 2lt7_A, 6a57_A, 2drp_D, 3uk3_C, 8cuc_F, 7y3l_A, 7txc_E, 1llm_D, 5yel_A, 4m9v_C, 7y3m_I, 8gn3_A, 7ej7_B, 5yj3_D
Binding Motifs: M0416_1.02 tgCGKGGGcg
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.