Transcription Factor
Accessions: | O14770 (JASPAR 2024) |
Names: | Homeobox protein Meis2, Meis1-related protein 1, MEIS2_HUMAN |
Organisms: | Homo sapiens |
Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
Uniprot: | O14770 |
Length: | |
Binding Motifs: | MA0774.1 tTGACAGs MA1640.1 raaTGATTTATgryy MA1640.2 TGATTTATg |
Binding Sites: | MA1640.1.1 MA1640.1.10 / MA1640.1.7 MA1640.1.11 MA1640.1.12 / MA1640.1.8 MA1640.1.13 / MA1640.1.9 MA1640.1.10 / MA1640.1.14 MA1640.1.11 / MA1640.1.15 MA1640.1.12 / MA1640.1.16 MA1640.1.13 / MA1640.1.17 MA1640.1.14 / MA1640.1.18 MA1640.1.15 / MA1640.1.19 MA1640.1.1 / MA1640.1.2 MA1640.1.16 / MA1640.1.20 MA1640.1.2 / MA1640.1.3 MA1640.1.4 MA1640.1.5 MA1640.1.6 MA1640.1.7 MA1640.1.8 MA1640.1.5 / MA1640.1.9 MA1640.1.17 MA1640.1.18 MA1640.1.19 MA1640.1.20 MA1640.1.3 MA1640.1.6 MA1640.2.5 MA1640.2.1 MA1640.2.10 MA1640.2.11 / MA1640.2.4 MA1640.2.12 MA1640.2.13 MA1640.2.14 / MA1640.2.17 MA1640.2.15 MA1640.2.16 MA1640.2.18 MA1640.2.19 MA1640.2.2 / MA1640.2.9 MA1640.2.20 MA1640.2.3 MA1640.2.6 MA1640.2.7 MA1640.2.8 |
Publications: | Knoepfler P. S., Calvo K. R., Chen H., Antonarakis S. E., Kamps M. P. Meis1 and pKnox1 bind DNA cooperatively with Pbx1 utilizing an interaction surface disrupted in oncoprotein E2a-Pbx1. Proc. Natl. Acad. Sci. USA 94:14553-14558 (1997). [Pubmed] Penkov D, Mateos San Martín D, Fernandez-Díaz LC, Rosselló CA, Torroja C, Sánchez-Cabo F, Warnatz HJ, Sultan M, Yaspo ML, Gabrieli A, Tkachuk V, Brendolan A, Blasi F, Torres M. Analysis of the DNA-binding profile and function of TALE homeoproteins reveals their specialization and specific interactions with Hox genes/proteins. Cell Rep 3:1321-33 (2013). [Pubmed] |
Related annotations: | PaperBLAST |
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