Transcription Factor
| Accessions: | NPAS2 (HT-SELEX2 May2017) |
| Names: | ENSG00000170485, NPAS2 |
| Organisms: | Homo sapiens |
| Libraries: | HT-SELEX2 May2017 1 1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed] |
| Notes: | TF family: bHLH experiment: HT-SELEX Hamming distance: 1 cycle: 3, TF family: bHLH experiment: Methyl-HT-SELEX Hamming distance: 1 cycle: 3 |
| Length: | 105 |
| Pfam Domains: | 8-55 Helix-loop-helix DNA-binding domain |
| Sequence: (in bold interface residues) | 1 EDEKDRAKRASRNKSEKKRRDQFNVLIKELSSMLPGNTRKMDKTTVLEKVIGFLQKHNEV 60 61 SAQTEICDIQQDWKPSFLSNEEFTQLMLEALDGFIIAVTTDGSII |
| Interface Residues: | 3, 7, 8, 9, 11, 12, 13, 14, 15, 16, 18, 19, 20, 43, 48 |
| 3D-footprint Homologues: | 4zpr_B, 5sy7_B, 1a0a_B, 1an4_A, 4zpk_B, 5eyo_A, 7xhv_B, 4zpk_A, 8osl_O, 7d8t_A, 7xi3_A, 5v0l_A, 7f2f_B, 4h10_A, 7xi3_B, 7ssa_L, 5nj8_D, 4h10_B, 8ia3_B, 6g1l_A, 8osl_P, 5gnj_I, 5nj8_C, 5v0l_B |
| Binding Motifs: | NPAS2_2 rmCACGTGyh NPAS2_methyl_1 rmCAyGyGyh |
| Related annotations: | PaperBLAST |
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