Transcription Factor

Accessions: 5vxn_D (3D-footprint 20231221)
Names: Capsular synthesis regulator component B, RCSB_ECOLI, Transcriptional regulatory protein RcsB
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Length: 197
Pfam Domains: 4-118 Response regulator receiver domain
138-193 Bacterial regulatory proteins, luxR family
Sequence:
(in bold interface residues)
1 NMNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINNLPKLDAHVLITDLSMPGD 60
61 KYGDGITLIKYIKRHFPSLSIIVLTMNNNPAILSAVLDLDIEGIVLKQGAPTDLPKALAA 120
121 LQKGKKESVSRLLEKIDKRLSPKESEVLRLFAEGFLVTEIAKKLNRSIKTISSQKKSAMM 180
181 KLGVENDIALLNYLSSV
Interface Residues: 89, 90, 91, 93, 94, 115, 167, 168, 169, 170, 172, 173, 174, 176
3D-footprint Homologues: 3zpl_B, 7ve5_B, 5w43_B, 4wuh_B, 1zlk_A, 6ide_A
Binding Motifs: 5vxn_CD TAGGAnnnnTCTTA
5vxn_D tAaGA
Binding Sites: 5vxn_G
5vxn_H
Publications: Filippova EV, Zemaitaitis B, Aung T, Wolfe AJ, Anderson WF. Structural Basis for DNA Recognition by the Two-Component Response Regulator RcsB. MBio : (2018). [Pubmed]
Related annotations: PaperBLAST

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