Transcription Factor

Accessions: 1hjb_A (3D-footprint 20231221)
Names: C/EBP beta, CCAAT/ENHANCER BINDING PROTEIN BETA, CCAAT/enhancer-binding protein beta, CEBPB_HUMAN, LAP, LIP, Liver activator protein, Liver-enriched inhibitory protein, Nuclear factor NF-IL6, TCF-5, Transcription factor 5
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P17676
Length: 66
Pfam Domains: 3-56 Basic region leucine zipper
4-62 bZIP transcription factor
Sequence:
(in bold interface residues)
1 DKHSDEYKIRRERNNIAVRKSRDKAKMRNLETQHKVLELTAENERLQKKVEQLSRELSTL 60
61 RNLFKQ
Interface Residues: 11, 14, 15, 17, 18, 21, 22
3D-footprint Homologues: 6mg1_B, 1nwq_C, 2c9l_Z, 2dgc_A
Binding Motifs: 1hjb_A gGaAA
1hjb_ABC TTTCCAAAnnnTGTGGTTG
Binding Sites: 1hjb_G
1hjb_H
Publications: Tahirov T.H, Inoue-Bungo T, Morii H, Fujikawa A, Sasaki M, Kimura K, Shiina M, Sato K, Kumasaka T, Yamamoto M, Ishii S, Ogata K. Structural analyses of DNA recognition by the AML1/Runx-1 Runt domain and its allosteric control by CBFbeta. Cell 104:755-67 (2001). [Pubmed]
Related annotations: PaperBLAST

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