Transcription Factor

Accessions: Q24256 (JASPAR 2024)
Names: BARH2_DROME, Homeobox protein B-H2, Homeobox protein BarH2
Organisms: Drosophila melanogaster
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q24256
Length: 645
Pfam Domains: 381-437 Homeobox domain
Sequence:
(in bold interface residues)
1 MTTMPPEMSATTAAPVGSAPSATAHHPAAVGGGMPRPASPAVGSNTTTATATTATRSRFM 60
61 ITDILAGAAAASAAAAAAAAALAAASSGGGRGSPTDSEREQSLVAQHHHHHQQQQQHHHH 120
121 QQQQQQQQHQQAALQQYIVQQQQLLRFEREREREREREHYRERHSPPGNNPYAHHPMPPH 180
181 LLAHFPPAHYAVLQQQQQQQQQQQHPHPHHLQLERERLEALHRHGHGLTGDPAQHLSHLS 240
241 HLSHQQHHPHLHHPMHDERSRSPLMLQQLGGNGGNNNNNNNNSSSASNNNNNNNNSASAN 300
301 SNIISGNSSSSNNNNGSGNGNMLLGGPGSSISGDQASTIDDSDSDDCGGKDDDGDDSMKN 360
361 GSSANGDSSSHLSLSLSKKQRKARTAFTDHQLQTLEKSFERQKYLSVQDRMELANKLELS 420
421 DCQVKTWYQNRRTKWKRQTAVGLELLAEAGNYAAFQRLYGGATPYLSAWPYAAAAAAQSP 480
481 HGATPSAIDIYYRQAAAAAAMQKPSLPASYRMYQSSIPPGMSLPGMPAPPPPGAAPMLSG 540
541 YYAAAAAAAASAGAQQQQQQPPAASRSPATSQSANSEADCERTSSSSRQRLITPSPPLNP 600
601 GSPPHRERINEEEDRERDEERDIERERERERERDEDDEEELALEV
Interface Residues: 380, 381, 382, 383, 384, 422, 423, 425, 426, 429, 430, 433, 434, 437
3D-footprint Homologues: 4j19_B, 2h1k_B, 1puf_A, 6a8r_A, 3cmy_A, 3d1n_M, 1fjl_B, 5zfz_A, 1ig7_A, 3lnq_A, 2lkx_A, 1jgg_B, 1nk2_P, 1zq3_P, 6m3d_C, 7q3o_C, 6es3_K, 2ld5_A, 3a01_E, 7psx_B, 5hod_A, 2hdd_A, 5jlw_D, 3rkq_B, 2r5y_A, 1puf_B, 1au7_A, 4xrs_G, 2hos_A, 4cyc_A, 1b72_A, 5flv_I, 3l1p_A, 5zjt_E, 1e3o_C, 7xrc_C, 2xsd_C, 1le8_A, 1le8_B, 1du0_A, 4qtr_D, 1mnm_C, 1k61_B, 1o4x_A, 8g87_X
Binding Motifs: MA0169.1 wTAATTG
Binding Sites: MA0169.1.7
MA0169.1.1
MA0169.1.10
MA0169.1.11
MA0169.1.12 / MA0169.1.16
MA0169.1.13
MA0169.1.14
MA0169.1.15
MA0169.1.17
MA0169.1.18 / MA0169.1.20
MA0169.1.19
MA0169.1.2
MA0169.1.3
MA0169.1.4
MA0169.1.5
MA0169.1.6
MA0169.1.8
MA0169.1.9
Publications: Noyes M.B, Meng X, Wakabayashi A, Sinha S, Brodsky M.H, Wolfe S.A. A systematic characterization of factors that regulate Drosophila segmentation via a bacterial one-hybrid system. Nucleic acids research 36:2547-60 (2008). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.