Transcription Factor

						

			
Accessions: 4j19_A (3D-footprint 20231221)

			
Names: HMBX1_HUMAN, Homeobox telomere-binding protein 1, Homeobox-containing protein 1, Telomere-associated homeobox-containing protein 1
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q6NT76
Length: 77
Pfam Domains:      3-71 Homeobox domain
    21-67 Homeobox KN domain
Sequence: 
(in bold interface residues)		   1 GSRFTWRKECLAVMESYFNENQYPDEAKREEIANACNAVIQKPGKKLSDLERVTSLKVYN   60
  61 WFANRRKEIKRRANIEA
Interface Residues: 2, 3, 56, 59, 60, 63, 64, 67, 68, 69, 70, 71
3D-footprint Homologues: 1k61_B, 2hdd_A, 3cmy_A, 4j19_B, 2hos_A, 1puf_B, 1fjl_B, 5zfz_A, 2h8r_B, 1ic8_B, 1mnm_C, 5jlw_D, 1ig7_A, 1le8_A, 5flv_I, 1nk2_P, 1du0_A, 6fqp_B, 3lnq_A, 6fqq_E, 4xrm_B, 2lkx_A, 3rkq_B, 4xrs_G, 3a01_E, 1b72_A, 6a8r_A, 4cyc_A
Binding Motifs: 4j19_AB GGTTAGGGTTAG
			
Publications: Kappei D, Butter F, Benda C, Scheibe M, Draškovič I, Stevense M, Novo C.L, Basquin C, Araki M, Araki K, Krastev D.B, Kittler R, Jessberger R, Londoño-Vallejo J.A, Mann M, Buchholz F. HOT1 is a mammalian direct telomere repeat-binding protein contributing to telomerase recruitment. The EMBO journal 32:1681-701 (2013). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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