Transcription Factor

Accessions: 1llm_D (3D-footprint 20231221)
Names: Amino acid biosynthesis regulatory protein, chimera of Zif23-GCN4, GCN4_YEAST, General control protein GCN4
Organisms: Saccharomyces cerevisiae, Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Length: 85
Pfam Domains: 4-26 C2H2-type zinc finger
4-26 Zinc finger, C2H2 type
18-42 Zinc-finger double domain
32-52 C2H2-type zinc finger
32-55 Zinc finger, C2H2 type
Sequence:
(in bold interface residues)
1 MKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHRDIQHILPIL 60
61 EDKVEELLSKNYHLENEVARLKKLV
Interface Residues: 4, 12, 14, 15, 16, 17, 18, 19, 20, 21, 22, 42, 43, 44, 45, 46, 47, 48, 49, 50, 52, 53, 54, 55, 70, 71, 72, 73, 76
3D-footprint Homologues: 2kmk_A, 2drp_D, 3uk3_C, 8cuc_F, 1g2f_F, 7y3l_A, 6ml4_A, 7eyi_G, 6a57_A, 5k5i_A, 8ssu_A, 5v3j_F, 2gli_A, 1llm_D, 7n5w_A, 6blw_A, 5kkq_D, 2lt7_A, 1ubd_C, 6u9q_A, 5yel_A, 4x9j_A, 2i13_A, 8h9h_G, 1mey_C, 7txc_E, 5kl3_A, 7ysf_A, 1f2i_J, 6wmi_A, 5ei9_F, 2jpa_A, 6jnm_A, 5und_A, 4m9v_C, 1tf6_A, 7y3m_I, 6e94_A, 8ssq_A, 1tf3_A, 7w1m_H, 8gn3_A, 2wbs_A, 5yj3_D, 2dgc_A
Binding Motifs: 1llm_CD cCCACGCGtGGG
1llm_D GCGkGGG
Binding Sites: 1llm_A / 1llm_B
Publications: Wolfe S.A, Grant R.A, Pabo C.O. Structure of a designed dimeric zinc finger protein bound to DNA. Biochemistry 42:13401-9 (2003). [Pubmed]
Related annotations: PaperBLAST

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