Transcription Factor
| Accessions: | UP00285A (UniPROBE 20160601) |
| Names: | AAS3, Amino acid biosynthesis regulatory protein, ARG9, Gcn4, General control protein GCN4, YEL009C |
| Organisms: | Saccharomyces cerevisiae |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | P03069 |
| Description: | Transcriptional activator of amino acid biosynthetic genes in response to amino acid starvation; expression is tightly regulated at both the transcriptional and translational levels |
| Length: | 74 |
| Pfam Domains: | 16-71 bZIP transcription factor 18-69 Basic region leucine zipper |
| Sequence: (in bold interface residues) | 1 MNRKQRSIPLSPIVPESSDPAALKRARNTEAARRSRARKLQRMKQLEDKVEELLSKNYHM 60 61 ENEVARLKKLVGER |
| Interface Residues: | 24, 25, 27, 28, 29, 30, 31, 32, 35, 36 |
| 3D-footprint Homologues: | 7x5e_F, 1nwq_C, 6mg1_B, 1llm_D, 5t01_B, 5vpe_D, 2dgc_A |
| Binding Motifs: | UP00285A_1 crwdrkrTGAsTCAymcwtmw |
| Binding Sites: | GTGACTCA TGACGTCA GTGACTAA ATGACACA ATGACGCA ATGACTAA ATGACTCA ATGAGTCA ATTAGTCA CTGACTCA CTGAGTCA GAGTCACA GAGTCATA GAGTCATC GTGACGCA GTGAGTCA GTGTCATA TGACTCAA TGAGTCAA AGTCATAC |
| Publications: | *Zhu C, *Byers K, *McCord RP, Shi Z, Berger MF, Newburger D, Saulrieta K, Smith Z, Shah M, Radhakrishnan M, Philippakis AA, Hu Y, De Masi F, Pacek M, Rolfs A , Murthy TVS, LaBaer J, Bulyk ML. High-Resolution DNA Binding Specificity Analysis of Yeast Transcription Factors. Genome Research. Epub January 21, 2009, doi:10.1101/gr.090233.108 (*co-1st authors). [Pubmed] |
| Related annotations: | PaperBLAST |
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