Transcription Factor
Accessions: | UP00504A (UniPROBE 20160601) |
Names: | Bagpipe, Bap, bgp, CG7902, Dmel\CG7902, dNK-3, Homeobox protein bagpipe, Homeobox protein NK-3, NK3 |
Organisms: | Drosophila melanogaster |
Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
Description: | Bagpipe: Bagpipe is expressed in a segmented pattern in visceral muscle and in a subset of cardiac muscles. It’s Loss of activity results in segmental gaps in midgut visceral muscle. |
Length: | 89 |
Pfam Domains: | 16-72 Homeobox domain |
Sequence: (in bold interface residues) | 1 SESPLSHDGSGLSRKKRSRAAFSHAQVFELERRFAQQRYLSGPERSEMAKSLRLTETQVK 60 61 IWFQNRRYKTKRKQIQQHEAALLGASKRV |
Interface Residues: | 16, 17, 18, 19, 57, 58, 60, 61, 64, 65, 67, 68, 69, 71, 72 |
3D-footprint Homologues: | 8pmf_A, 8ejp_B, 1zq3_P, 6m3d_C, 2lkx_A, 7q3o_C, 6es3_K, 2ld5_A, 8osb_E, 2hos_A, 8eml_B, 9b8u_A, 7psx_B, 2hdd_A, 4cyc_A, 8ik5_C, 7xrc_C, 2h8r_B, 8g87_X, 8bx1_A |
Binding Motifs: | UP00504A_1 GrayyrrCCACTTAryyytgaw |
Binding Sites: | AAGTACTT ACACTTAA ACCACTTA ACTTAAGT AGCACTTA AGTACTTA ATAAGTGG CACTTAAA CACTTAAC CACTTAAG CCACTTAA CCACTTAC CCACTTAG CCCACTTA GCACTTAA GCCACTTA GGCACTTA GGTACTTA GTACTTAA TAAGTGGA |
Publications: | Busser BW, Shokri L, Jaeger SA, Gisselbrecht SS, Singhania A, Berger MF, Zhou B, Bulyk ML, Michelson AM. Molecular mechanism underlying the regulatory specificity of a Drosophila homeodomain protein that specifies myoblast identity. Development 139:1164-74 (2012). [Pubmed] |
Related annotations: | PaperBLAST |
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