Transcription Factor

Accessions: Q7L945 (JASPAR 2024)
Names: ZN627_HUMAN
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q7L945
Length: 461
Pfam Domains: 4-44 KRAB box
147-176 Zinc-finger double domain
167-189 Zinc finger, C2H2 type
167-189 C2H2-type zinc finger
167-191 C2H2-type zinc finger
183-205 Zinc-finger double domain
194-206 C2H2-type zinc finger
195-217 Zinc finger, C2H2 type
195-217 C2H2-type zinc finger
210-234 Zinc-finger double domain
222-233 C2H2-type zinc finger
223-245 C2H2-type zinc finger
239-262 Zinc-finger double domain
250-261 C2H2-type zinc finger
251-273 C2H2-type zinc finger
267-289 Zinc-finger double domain
278-289 C2H2-type zinc finger
279-301 C2H2-type zinc finger
294-315 Zinc-finger double domain
307-329 C2H2-type zinc finger
322-344 Zinc-finger double domain
334-345 C2H2-type zinc finger
335-357 Zinc finger, C2H2 type
335-357 C2H2-type zinc finger
350-374 Zinc-finger double domain
363-385 C2H2-type zinc finger
363-381 C2H2-type zinc finger
377-402 Zinc-finger double domain
390-402 C2H2-type zinc finger
391-413 C2H2-type zinc finger
391-413 Zinc finger, C2H2 type
406-430 Zinc-finger double domain
418-437 C2H2-type zinc finger
419-441 C2H2-type zinc finger
419-441 Zinc finger, C2H2 type
Sequence:
(in bold interface residues)
1 MDSVAFEDVAVNFTLEEWALLDPSQKNLYRDVMRETFRNLASVGKQWEDQNIEDPFKIPR 60
61 RNISHIPERLCESKEGGQGEETFSQIPDGILNKKTPGVKPCESSVCGEVGMGPSSLNRHI 120
121 RDHTGREPNEYQEYGKKSYTRNQCGRALSYHRSFPVRERTHPGGKPYDCKECGETFISLV 180
181 SIRRHMLTHRGGVPYKCKVCGKAFDYPSLFRIHERSHTGEKPYECKQCGKAFSCSSYIRI 240
241 HERTHTGDKPYECKQCGKAFSCSKYIRIHERTHTGEKPYECKQCGKAFRCASSVRSHERT 300
301 HTGEKLFECKECGKALTCLASVRRHMIKHTGNGPYKCKVCGKAFDFPSSFRIHERTHTGE 360
361 KPYDCKQCGKAFSCSSSFRKHERIHTGEKPYKCTKCGKAFSRSSYFRIHERTHTGEKPYE 420
421 CKQCGKAFSRSTYFRVHEKIHTGEKPYENPNPNASVVPVLS
Interface Residues: 178, 180, 181, 184, 205, 206, 208, 209, 212, 233, 234, 235, 236, 237, 240, 244, 261, 262, 263, 264, 265, 268, 289, 290, 291, 292, 293, 294, 295, 296, 297, 317, 318, 319, 320, 321, 322, 323, 324, 325, 335, 345, 346, 347, 348, 349, 351, 352, 354, 355, 358, 373, 374, 375, 376, 377, 379, 380, 386, 400, 401, 402, 403, 404, 405, 407, 408, 412, 429, 430, 431, 432, 433, 436
3D-footprint Homologues: 7w1m_H, 5yel_A, 7y3m_I, 6e94_A, 6jnm_A, 7y3l_A, 2gli_A, 5ei9_F, 5v3j_F, 8ssq_A, 8ssu_A, 1tf3_A, 3uk3_C, 1tf6_A, 6a57_A, 5kkq_D, 4m9v_C, 6ml4_A, 2kmk_A, 5k5i_A, 6u9q_A, 7ysf_A, 2jpa_A, 1ubd_C, 7n5w_A, 8gn3_A, 4x9j_A, 1f2i_J, 5kl3_A, 7txc_E, 1g2f_F, 6blw_A, 8h9h_G, 2lt7_A, 8cuc_F, 2wbs_A, 1llm_D, 2drp_D, 5yj3_D
Binding Motifs: UN0644.1 GrTCTCAACAaw
UN0644.2 GrTCTCAACA
Binding Sites: UN0644.1.1
UN0644.1.10
UN0644.1.11
UN0644.1.12 / UN0644.1.13
UN0644.1.13 / UN0644.1.14
UN0644.1.14 / UN0644.1.15
UN0644.1.15 / UN0644.1.16
UN0644.1.16 / UN0644.1.17
UN0644.1.17 / UN0644.1.18
UN0644.1.18 / UN0644.1.20
UN0644.1.19
UN0644.1.2
UN0644.1.20
UN0644.1.3 / UN0644.1.4
UN0644.1.4 / UN0644.1.5
UN0644.1.5 / UN0644.1.6
UN0644.1.6 / UN0644.1.7
UN0644.1.7
UN0644.1.8
UN0644.1.9
UN0644.1.12
UN0644.1.19
UN0644.1.2
UN0644.1.3
UN0644.2.1
UN0644.2.10
UN0644.2.11 / UN0644.2.4
UN0644.2.12
UN0644.2.13 / UN0644.2.6
UN0644.2.14
UN0644.2.15 / UN0644.2.9
UN0644.2.16
UN0644.2.17
UN0644.2.18
UN0644.2.19
UN0644.2.2
UN0644.2.20
UN0644.2.3
UN0644.2.5
UN0644.2.7
UN0644.2.8
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.