Transcription Factor

						

			
Accessions: 3tmm_A (3D-footprint 20231221)

			
Names: Mitochondrial transcription factor 1, MtTF1, mtTFA, TCF-6, TFAM_HUMAN, Transcription factor 6, Transcription factor 6-like 2, Transcription factor A, mitochondrial
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q00059
Length: 195
Pfam Domains:      8-76 HMG (high mobility group) box
     8-70 Domain of unknown function (DUF1898)
  112-173 Domain of unknown function (DUF1898)
  113-176 HMG (high mobility group) box
Sequence: 
(in bold interface residues)		   1 SSVLASCPKKPVSSYLRFSKEQLPIFKAQNPDAKTTELIRRIAQRWRELPDSKKKIYQDA   60
  61 YRAEWQVYKEEISRFKEQLTPSQIMSLEKEIMDKHLKRKAMTKKKELTLLGKPKRPRSAY  120
 121 NVYVAERFQEAKGDSPQEKLKTVKENWKNLSDSEKELYIQHAKEDETRYHNEMKSWEEQM  180
 181 IEVGRKDLLRRTIKK
Interface Residues: 10, 13, 15, 16, 19, 23, 34, 35, 36, 39, 97, 98, 99, 101, 104, 105, 115, 120, 121, 124, 128, 136, 137, 140
3D-footprint Homologues: 3f27_D, 4y60_C, 1o4x_B, 3tmm_A, 6jrp_D, 1qrv_A, 2gzk_A, 3u2b_C, 1j5n_A, 3tq6_B, 1hry_A, 1ckt_A, 7zie_A
Binding Motifs: 3tmm_A AGTTGGnnnnnGnCTGT
Binding Sites: 3tmm_B
3tmm_C
			
Publications: Ngo H.B, Kaiser J.T, Chan D.C. The mitochondrial transcription and packaging factor Tfam imposes a U-turn on mitochondrial DNA. Nature structural & molecular biology 18:1290-6 (2011). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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