Transcription Factor

Accessions: 4cn5_A (3D-footprint 20231221)
Names: Nuclear receptor subfamily 2 group B member 1, RETINOIC ACID RECEPTOR RXR-ALPHA, Retinoid X receptor alpha, RXRA_HUMAN
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P19793
Length: 81
Pfam Domains: 6-74 Zinc finger, C4 type (two domains)
Sequence:
(in bold interface residues)
1 MFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQ 60
61 YCRYQKCLAMGMKREAVQEER
Interface Residues: 15, 16, 18, 19, 25, 26, 28, 29, 32, 33, 57, 79, 81
3D-footprint Homologues: 6fbq_A, 7wnh_D, 6l6q_B, 3g9m_B, 1a6y_A, 1lo1_A, 4oln_B, 2han_B, 1kb2_B, 2a66_A, 2nll_B, 1lat_A, 7xv6_B, 2ff0_A, 1dsz_A, 4umm_E, 3cbb_A, 8cef_H, 4iqr_B, 2han_A, 1hcq_E, 8hbm_B, 5krb_G, 5cbz_E, 4tnt_B, 5e69_A, 4hn5_B, 5emc_A, 7prw_B, 5cbx_B, 3g6t_A, 1r4i_A
Binding Motifs: 4cn5_A GGTCAnnG
4cn5_AB TGAACynTGACCC
Binding Sites: 4cn5_C
4cn5_D
Publications: Osz J, McEwen A.G, Poussin-Courmontagne P, Moutier E, Birck C, Davidson I, Moras D, Rochel N. Structural basis of natural promoter recognition by the retinoid X nuclear receptor. Scientific reports 5:8216 (2015). [Pubmed]
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.