Transcription Factor

Accessions: T099687_1.02 (CISBP 1.02), G5EE18 (JASPAR 2024)
Names: ceh-28, T099687_1.02;, CEH28_CAEEL, G5EE18_CAEEL, Homeobox domain-containing protein, Homeobox protein ceh-28, NK-2 family homeodomain protein CEH-28, NK-2 homeodomain factor CEH-28
Organisms: Caenorhabditis elegans
Libraries: CISBP 1.02 1, JASPAR 2024 2
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: experiment type:ChIP-seq, family:Homeodomain
Length: 201
Pfam Domains: 105-161 Homeobox domain
Sequence:
(in bold interface residues)
1 MQSTQISSTTVILPSEVIQPPQQSAVPSEFKNTLPSRLNLFEGFDQSFSELTNPYQPVIP 60
61 LMQRESLLGASSYYSSPSQNQRSYQNHRQHSNPDTINLRSQQQKRKPRVLFTQHQVNELE 120
121 ERFKKQRYVTATEREELAQCLGLTATQVKIWFQNRRYKCKRLAQDRTLQLSQIPFNPMFA 180
181 SAFPFGINSFGTAPSSSSSGS
Interface Residues: 79, 80, 83, 102, 104, 105, 106, 107, 108, 146, 147, 149, 150, 153, 154, 156, 157, 158, 160, 161
3D-footprint Homologues: 5zfz_A, 1puf_A, 4j19_B, 5zjt_E, 8ejp_B, 1fjl_B, 6a8r_A, 3cmy_A, 1ig7_A, 3d1n_M, 8pmf_A, 3lnq_A, 1nk2_P, 1zq3_P, 1au7_A, 2lkx_A, 6m3d_C, 2ld5_A, 7q3o_C, 6es3_K, 5flv_I, 9b8u_A, 3a01_E, 8ik5_C, 7psx_B, 5hod_A, 3rkq_B, 2hdd_A, 8osb_E, 1b72_A, 4cyc_A, 2r5y_A, 8eml_B, 4xrs_G, 2hos_A, 1jgg_B, 5jlw_D, 1e3o_C, 1le8_A, 7xrc_C, 2xsd_C, 8bx1_A, 4qtr_D, 1k61_B, 1o4x_A, 4xrm_B, 1mnm_C, 1du0_A, 1puf_B, 8g87_X
Binding Motifs: M4717_1.02 AATCGATw
MA1445.1 wwATCGATww
Binding Sites: MA1445.1.1 / MA1445.1.19 / MA1445.1.9
MA1445.1.10 / MA1445.1.2 / MA1445.1.20
MA1445.1.11 / MA1445.1.14 / MA1445.1.16 / MA1445.1.4 / MA1445.1.5 / MA1445.1.8
MA1445.1.12 / MA1445.1.13 / MA1445.1.15 / MA1445.1.3 / MA1445.1.6 / MA1445.1.7
MA1445.1.17
MA1445.1.18
Publications: Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Related annotations: PaperBLAST

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