Transcription Factor
| Accessions: | TEAD1 (HT-SELEX2 May2017) |
| Names: | ENSG00000187079, TEAD1 |
| Organisms: | Homo sapiens |
| Libraries: | HT-SELEX2 May2017 1 1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed] |
| Notes: | TF family: TEA experiment: HT-SELEX Hamming distance: 1 cycle: 3, TF family: TEA experiment: Methyl-HT-SELEX Hamming distance: 1 cycle: 3 |
| Length: | 426 |
| Pfam Domains: | 9-418 TEA/ATTS domain family |
| Sequence: (in bold interface residues) | 1 IEPSSWSGSESPAENMERMSDSADKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIIL 60 61 SDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRDFHSKLKDQTAKDKALQ 120 121 HMAAMSSAQIVSATAIHNKLGLPGIPRPTFPGAPGFWPGMIQTGQPGSSQDVKPFVQQAY 180 181 PIQPAVTAPIPGFEPASAPAPSVPAWQGRSIGTTKLRLVEFSAFLEQQRDPDSYNKHLFV 240 241 HIGHANHSYSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFFLVKFWADLNCNIQD 300 301 DAGAFYGVTSQYESSENMTVTCSTKVCSFGKQVVEKVETEYARFENGRFVYRINRSPMCE 360 361 YMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHI 420 421 YRLVKD |
| Interface Residues: | 66, 70, 87, 88, 91, 92, 95, 96, 99, 200, 204 |
| 3D-footprint Homologues: | 5gzb_A, 5no6_N, 1oe4_B |
| Binding Motifs: | TEAD1_2 crCATwCCr TEAD1_methyl_1 crCATwCCd |
| Related annotations: | PaperBLAST |
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