Transcription Factor
| Accessions: | O16850 (JASPAR 2024) |
| Names: | Abnormal dauer formation protein 16, Forkhead box protein O, FOXO_CAEEL |
| Organisms: | Caenorhabditis elegans |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | O16850 |
| Length: | 541 |
| Pfam Domains: | 178-263 Fork head domain |
| Sequence: (in bold interface residues) | 1 MQLEQKSSLHCSKCRNFLQKFSQDMQAWNCRELDSPLPSDITLHNLEPARPDSGMSFSTD 60 61 FDDDFFNLDLHQQERSASFGGVTQYSQQFLREKCSFSPYFHTSLETVDSGRTSLYGSNEQ 120 121 CGQLGGASSNGSTAMLHTPDGSNSHQTSFPSDFRMSESPDDTVSGKKTTTRRNAWGNMSY 180 181 AELITTAIMASPEKRLTLAQVYEWMVQNVPYFRDKGDSNSSAGWKNSIRHNLSLHSRFMR 240 241 IQNEGAGKSSWWVINPDAKPGRNPRRTRERSNTIETTTKAQLEKSRRGAKKRIKERALMG 300 301 SLHSTLNGNSIAGSIQTISHDLYDDDSMQGAFDNVPSSFRPRTQSNLSIPGSSSRVSPAI 360 361 GSDIYDDLEFPSWVGESVPAIPSDIVDRTDQMRIDATTHIGGVQIKQESKPIKTEPIAPP 420 421 PSYHELNSVRGSCAQNPLLRNPIVPSTNFKPMPLPGAYGNYQNGGITPINWLSTSNSSPL 480 481 PGIQSCGIVAAQHTVASSSALPIDLENLTLPDQPLMDTMDVDALIRHELSQAGGQHIHFD 540 541 L |
| Interface Residues: | 220, 223, 225, 226, 227, 229, 230, 231, 233, 234, 243, 248, 266 |
| 3D-footprint Homologues: | 3l2c_A, 7vox_H, 2hdc_A, 6el8_A, 7tdx_A, 7yzb_A, 6nce_A, 2uzk_A, 7vou_C, 2a07_J, 7yze_A, 7cby_C, 3co6_C, 6ako_C, 2c6y_A, 7yzg_A, 7tdw_A, 3g73_A, 7yz7_A, 3qrf_G |
| Binding Motifs: | MA1446.1 wtGTAAACAcaw MA1446.2 GTAAACAc |
| Binding Sites: | MA1446.2.11 / MA1446.2.4 / MA1446.2.6 / MA1446.2.9 MA1446.2.18 MA1446.2.10 / MA1446.2.17 / MA1446.2.3 / MA1446.2.7 MA1446.2.16 MA1446.2.1 / MA1446.2.15 MA1446.1.1 MA1446.1.10 MA1446.1.11 / MA1446.1.7 MA1446.1.12 / MA1446.1.8 MA1446.1.13 / MA1446.1.9 MA1446.1.14 MA1446.1.10 / MA1446.1.15 MA1446.1.16 MA1446.1.11 / MA1446.1.17 MA1446.1.18 MA1446.1.19 MA1446.1.2 MA1446.1.12 / MA1446.1.20 MA1446.1.3 MA1446.1.4 MA1446.1.5 MA1446.1.6 MA1446.1.6 / MA1446.1.7 MA1446.1.8 MA1446.1.9 MA1446.1.13 MA1446.1.14 MA1446.1.15 MA1446.1.16 MA1446.1.17 MA1446.1.18 MA1446.1.19 MA1446.1.20 MA1446.1.5 MA1446.2.20 MA1446.2.12 MA1446.2.13 / MA1446.2.2 / MA1446.2.8 MA1446.2.14 MA1446.2.19 MA1446.2.5 |
| Publications: | Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] |
| Related annotations: | PaperBLAST |
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