Transcription Factor

						

			
Accessions: Q96T25 (JASPAR 2024)

			
Names: ZIC5_HUMAN, Zinc finger protein of the cerebellum 5, Zinc finger protein ZIC 5
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q96T25
Length: 663
Pfam Domains:   480-503 Zinc-finger double domain
  491-515 Zinc finger, C2H2 type
  491-515 C2H2-type zinc finger
  507-534 Zinc-finger double domain
  521-545 C2H2-type zinc finger
  551-575 C2H2-type zinc finger
  551-575 Zinc finger, C2H2 type
Sequence: 
(in bold interface residues)		   1 MFLKAGRGNKVPPVRVYGPDCVVLMEPPLSKRNPPALRLADLATAQVQPLQNMTGFPALA   60
  61 GPPAHSQLRAAVAHLRLRDLGADPGVATTPLGPEHMAQASTLGLSPPSQAFPAHPEAPAA  120
 121 AARAAALVAHPGAGSYPCGGGSSGAQPSAPPPPAPPLPPTPSPPPPPPPPPPPALSGYTT  180
 181 TNSGGGGSSGKGHSRDFVLRRDLSATAPAAAMHGAPLGGEQRSGTGSPQHPAPPPHSAGM  240
 241 FISASGTYAGPDGSGGPALFPALHDTPGAPGGHPHPLNGQMRLGLAAAAAAAAAELYGRA  300
 301 EPPFAPRSGDAHYGAVAAAAAAALHGYGAVNLNLNLAAAAAAAAAGPGPHLQHHAPPPAP  360
 361 PPPPAPAQHPHQHHPHLPGAAGAFLRYMRQPIKQELICKWIDPDELAGLPPPPPPPPPPP  420
 421 PPPPAGGAKPCSKTFGTMHELVNHVTVEHVGGPEQSSHVCFWEDCPREGKPFKAKYKLIN  480
 481 HIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFDGCDRKFANSSDRKK  540
 541 HSHVHTSDKPYYCKIRGCDKSYTHPSSLRKHMKIHCKSPPPSPGPLGYSSVGTPVGAPLS  600
 601 PVLDPARSHSSTLSPQVTNLNEWYVCQASGAPSHLHTPSSNGTTSETEDEEIYGNPEVVR  660
 661 TIH
Interface Residues: 443, 467, 469, 473, 474, 475, 476, 477, 479, 480, 482, 483, 484, 486, 503, 504, 505, 506, 507, 509, 510, 511, 533, 534, 535, 536, 537, 538, 539, 540, 541, 543, 544, 564, 565, 566, 567, 568, 569, 570
3D-footprint Homologues: 1ubd_C, 7w1m_H, 1tf3_A, 7n5w_A, 5v3j_F, 5yel_A, 4x9j_A, 2gli_A, 5kkq_D, 1tf6_A, 8gn3_A, 5ei9_F, 1g2f_F, 2kmk_A, 6ml4_A, 8h9h_G, 6e94_A, 5k5i_A, 2lt7_A, 2jpa_A, 8cuc_F, 7y3l_A, 6jnm_A, 3uk3_C, 6blw_A, 6u9q_A, 1f2i_J, 5kl3_A, 7txc_E, 1llm_D, 7ysf_A, 2drp_D, 8ssq_A, 4m9v_C, 7y3m_I, 6a57_A, 5k5l_F, 2wbs_A, 5yj3_D
Binding Motifs: MA1584.1 mgACCCCCCGCtGyGm
MA1584.2 gACCCCCCGCtGyGm
			
Publications: Weirauch MT, Cote A, Norel R, Annala M, Zhao Y, Riley TR, Saez-Rodriguez J, Cokelaer T, Vedenko A, Talukder S; DREAM5 Consortium, Bussemaker HJ, Morris QD, Bulyk ML, Stolovitzky G, Hughes TR. Evaluation of methods for modeling transcription factor sequence specificity. Nat Biotechnol 31:126-34 (2013). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.