Transcription Factor
| Accessions: | UP00203A (UniPROBE 20160601) |
| Names: | D17Wsu76e, Homeobox protein PKNOX1, Pbx/knotted 1 homeobox, PBX/knotted homeobox 1, Pknox1, PREP1 |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | O70477 |
| Description: | Pbx/knotted 1 homeobox |
| Length: | 96 |
| Pfam Domains: | 34-73 Homeobox KN domain 35-73 Homeobox domain |
| Sequence: (in bold interface residues) | 1 QLNQDLSILHQEDGSSKNKRGVLPKHATNVMRSWLFQHIGHPYPTEDEKKQIAAQTNLTL 60 61 LQVNNWFINARRRILQPMLDSSCSETPKTKKKPAQN |
| Interface Residues: | 17, 19, 20, 22, 61, 62, 64, 65, 68, 69, 70, 72, 73 |
| 3D-footprint Homologues: | 1puf_A, 6fqp_B, 4j19_B, 1puf_B, 1mnm_C, 2ld5_A, 1le8_A, 1au7_A, 6fqq_E, 3rkq_B, 5flv_I, 7psx_B, 5hod_A, 2lkx_A, 1le8_B, 4xrm_B, 1zq3_P, 1fjl_B, 3cmy_A, 4xrs_G, 2d5v_B, 1k61_B |
| Binding Motifs: | UP00203A_1 wrmsAsCTGTCAawmc |
| Binding Sites: | AACTGTCA AATGACAG ACCTGTCA AGCTGTCA AGTGACAG ATCTGTCA ATGACAGC ATGACAGG ATTGACAG CCTGTCAA CCTGTCAC CCTGTCAG CTGACAGC CTGTCAAA CTGTCACA CTGTCAGA GCCTGTCA GCTGTCAA GCTGTCAC GGCTGTCA |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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