Transcription Factor
| Accessions: | Q9CXE0 (JASPAR 2024) |
| Names: | EC 2.1.1.-, PR domain zinc finger protein 5, PR domain-containing protein 5, PRDM5_MOUSE |
| Organisms: | Mus musculus |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q9CXE0 |
| Length: | 599 |
| Pfam Domains: | 167-190 C2H2-type zinc finger 167-188 C2H2-type zinc finger 182-208 Zinc-finger double domain 199-221 Zinc finger, C2H2 type 199-222 C2H2-type zinc finger 199-221 C2H2-type zinc finger 231-256 Zinc finger, C2H2 type 231-256 C2H2-type zinc finger 265-282 Zinc-finger of C2H2 type 265-284 C2H2-type zinc finger 289-311 C2H2-type zinc finger 304-328 Zinc-finger double domain 317-336 C2H2-type zinc finger 317-339 Zinc finger, C2H2 type 317-335 C2H2-type zinc finger 335-356 Zinc-finger double domain 345-368 C2H2-type zinc finger 345-367 Zinc finger, C2H2 type 345-365 Zinc-finger of C2H2 type 345-367 C2H2-type zinc finger 360-383 Zinc-finger double domain 373-384 C2H2-type zinc finger 373-395 C2H2-type zinc finger 387-412 Zinc-finger double domain 400-411 C2H2-type zinc finger 401-424 C2H2-type zinc finger 401-424 Zinc finger, C2H2 type 416-441 Zinc-finger double domain 430-452 C2H2-type zinc finger 430-452 Zinc finger, C2H2 type 430-450 Zinc-finger of C2H2 type 430-452 C2H2-type zinc finger 445-468 Zinc-finger double domain 459-480 Zinc finger, C2H2 type 460-480 C2H2-type zinc finger 460-480 C2H2-type zinc finger 473-496 Zinc-finger double domain 486-508 C2H2-type zinc finger 486-508 Zinc finger, C2H2 type 501-524 Zinc-finger double domain 514-536 Zinc finger, C2H2 type 514-536 C2H2-type zinc finger 514-536 C2H2-type zinc finger 529-552 Zinc-finger double domain 542-564 Zinc finger, C2H2 type 542-565 C2H2-type zinc finger 572-594 Zinc finger, C2H2 type 573-594 C2H2-type zinc finger |
| Sequence: (in bold interface residues) | 1 MLGMYVPDRFALKSSRVQDGMGLYTARRVRKGEKFGPFAGEKRMPEDLDENMDYRLMWEV 60 61 RGSKGEVLYILDATNPRHSNWLRFVHEAPSQERKNLAAIQEGENIFYLAVDDIETDTELL 120 121 IGYLDSDVEAEEEEQQALTMTKEGKVDHSKGQLAAGSKGHLGCEEDFACPQCESSFPSEE 180 181 VLTEHLQSLHQKPTGEKEFKCENCGKKFPVRQALQRHFEQHRKACRGEARFVCKADSCGK 240 241 RLKSKDALRRHQENVHTGDPKRKLICSVCNRKCTSVSSLQEHRKIHEIFDCQECMKKFIS 300 301 ANQLKRHMITHSEKRPYNCEICNKSFKRLDQVGAHKVIHSEDKPYQCKLCGKGFAHRNVY 360 361 KNHKKTHSEERPFQCDACKALFRTPFSLQRHLLIHNSERTFKCHHCDATFKRKDTLNVHV 420 421 QVVHERHKKYRCELCNKAFVTPSVLRSHKKTHTGEKEKVCPYCGQKFASSGTLRVHIRSH 480 481 TGERPYQCPYCEKGFSKNDGLKMHIRTHTREKPYQCSECSKAFSQKRGLDEHKRTHTGEK 540 541 PFQCDVCDLAFSLKKMLIRHKMTHNPNRPMAECHFCHKKFTRNDYLKVHMDNIHGVADS |
| Interface Residues: | 275, 277, 281, 299, 302, 303, 306, 328, 329, 330, 331, 334, 338, 355, 356, 358, 359, 362, 384, 385, 386, 387, 390, 412, 414, 415, 418, 440, 441, 443, 444, 446, 447, 468, 469, 470, 471, 472, 474, 475, 477, 478, 479, 481, 496, 497, 498, 499, 500, 503, 509, 523, 524, 525, 526, 527, 528, 531, 535, 552, 553, 554, 555, 556, 558, 559, 562, 582, 584, 585 |
| 3D-footprint Homologues: | 7w1m_H, 7ysf_A, 8ssq_A, 8ssu_A, 5v3j_F, 1ubd_C, 2lt7_A, 7y3m_I, 6e94_A, 7n5w_A, 2gli_A, 2kmk_A, 6u9q_A, 8h9h_G, 2jpa_A, 1tf3_A, 1tf6_A, 8gh6_A, 7y3l_A, 8cuc_F, 8gn3_A, 7txc_E, 2drp_D |
| Binding Motifs: | MA1999.1 ctGTTCTCCATCtss MA1999.2 GTTCTCCATCt |
| Binding Sites: | MA1999.1.1 MA1999.1.10 MA1999.1.11 / MA1999.1.20 MA1999.1.12 MA1999.1.13 MA1999.1.14 MA1999.1.15 MA1999.1.16 MA1999.1.17 MA1999.1.18 MA1999.1.19 MA1999.1.2 / MA1999.1.4 MA1999.1.20 MA1999.1.3 / MA1999.1.5 MA1999.1.4 / MA1999.1.7 MA1999.1.5 / MA1999.1.8 MA1999.1.10 / MA1999.1.6 MA1999.1.11 / MA1999.1.7 MA1999.1.13 / MA1999.1.8 MA1999.1.17 / MA1999.1.9 MA1999.1.12 MA1999.1.14 MA1999.1.15 MA1999.1.16 MA1999.1.18 MA1999.1.19 MA1999.1.2 MA1999.1.3 MA1999.1.6 MA1999.1.9 MA1999.2.1 MA1999.2.10 MA1999.2.11 MA1999.2.12 MA1999.2.13 MA1999.2.14 MA1999.2.15 MA1999.2.16 MA1999.2.17 MA1999.2.18 MA1999.2.19 MA1999.2.2 MA1999.2.20 MA1999.2.3 MA1999.2.4 MA1999.2.5 MA1999.2.6 MA1999.2.7 MA1999.2.8 MA1999.2.9 |
| Publications: | Galli GG, Honnens de Lichtenberg K, Carrara M, Hans W, Wuelling M, Mentz B, Multhaupt HA, Fog CK, Jensen KT, Rappsilber J, Vortkamp A, Coulton L, Fuchs H, Gailus-Durner V, Hrabě de Angelis M, Calogero RA, Couchman JR, Lund AH. Prdm5 regulates collagen gene transcription by association with RNA polymerase II in developing bone. PLoS Genet : (2012;8(5):e1002711.). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.