Transcription Factor

Accessions: MSGN1 (HT-SELEX2 May2017)
Names: ENSG00000151379, MSGN1
Organisms: Homo sapiens
Libraries: HT-SELEX2 May2017 1
1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]
Notes: TF family: bHLH experiment: HT-SELEX Hamming distance: 1 cycle: 2, TF family: bHLH experiment: Methyl-HT-SELEX Hamming distance: 1 cycle: 2
Length: 94
Pfam Domains: 27-80 Helix-loop-helix DNA-binding domain
Sequence:
(in bold interface residues)
1 AFQPTHLQGGGGPKAQKGTKVRMSVQRRRKASEREKLRMRTLADALHTLRNYLPPVYSQR 60
61 GQPLTKIQTLKYTIKYIGELTDLLNRGREPRAQS
Interface Residues: 28, 32, 34, 35, 38, 39
3D-footprint Homologues: 8osb_B, 2ypa_A, 7z5k_B, 2ql2_D, 5eyo_A
Binding Motifs: MSGN1_2 srCCAwwTGkys
MSGN1_methyl_1 brcCAwwTGkyv
Related annotations: PaperBLAST

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