Transcription Factor
| Accessions: | FOXG1_DBD (HumanTF 1.0), FOXJ3_DBD (HumanTF 1.0) |
| Names: | BF-1, BF-2, BF1, BF2, Brain factor 1, Brain factor 2, Forkhead box protein G1, Forkhead box protein G1A, Forkhead box protein G1B, Forkhead box protein G1C, Forkhead-related protein FKHL1, Forkhead-related protein FKHL2, Forkhead-related protein FKHL3, FOXG1, FOXG1_HUMAN, hBF-2, HFK1, HFK2, HFK3, FOXJ3, FOXJ3_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | HumanTF 1.0 1 1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] |
| Uniprot: | P55316 |
| Notes: | Ensembl ID: ENSG00000176165; DNA-binding domain sequence; TF family: Forkhead; Clone source: MGC, Ensembl ID: ENSG00000198815; DNA-binding domain sequence; TF family: Forkhead; Clone source: Megaman |
| Length: | 137 |
| Pfam Domains: | 21-116 Fork head domain |
| Sequence: (in bold interface residues) | 1 MAGKDGEGGKEGEKKNGKYEKPPFSYNALIMMAIRQSPEKRLTLNGIYEFIMKNFPYYRE 60 61 NKQGWQNSIRHNLSLNKCFVKVPRHYDDPGKGNYWMLDPSSDDVFIGGTTGKLRRRSTTS 120 121 PAKLAFKRGAALTSTGL |
| Interface Residues: | 14, 16, 18, 44, 61, 63, 64, 66, 67, 68, 70, 71, 72, 74, 75, 84, 91, 112, 116 |
| 3D-footprint Homologues: | 7yz7_A, 7yzb_A, 7yzg_A, 8vfz_O, 3l2c_A, 8bzm_E, 7vox_H, 2hdc_A, 2a07_J, 7yze_A, 7cby_C, 3co6_C, 6ako_C, 2c6y_A, 7tdw_A, 3g73_A, 6el8_A, 7tdx_A, 6nce_A, 2uzk_A, 7vou_C, 3qrf_G, 8sro_B |
| Binding Motifs: | FOXG1_DBD_1 rTAAACAATdGTAAACA FOXG1_DBD_2 rCGGACACAATr FOXJ3_DBD_1 rTAAAcAA FOXJ3_DBD_2 GTAAACArTAAACA FOXJ3_DBD_3 GTAAACATAAACA |
| Publications: | Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] |
| Related annotations: | PaperBLAST |
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