Transcription Factor

Accessions: T016874_1.02 (CISBP 1.02)
Names: crp, T016874_1.02;
Organisms: Drosophila melanogaster
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:B1H, family:bHLH
Length: 631
Pfam Domains: 97-147 Helix-loop-helix DNA-binding domain
Sequence:
(in bold interface residues)
1 MSAVPVAIKTEEVILEHAEYNSAEELDEELQLQLEDSGGENYHIEFASESAHQGSQRRQS 60
61 SMSGTNTSKGGGGGGSGALSDGDGSGKPLVDSEKRMRREIANSNERRRMQSINAGFQSLR 120
121 SLLPRHEGEKLSKAAILQQTFQYIVELENQKTQLLTQNSELKRQVGEHEAGGSGDGGGTN 180
181 SGGNYNDSNASGGNSTAVAIKKRKLTDNVINIQAISDSSDEGLGSMSPEPMTLLTAGGAA 240
241 ATKLSNAATLLAAKELHESKKQLEKERSLRRLLEDELQMIKRQLYSVATAPPGTAVAAAS 300
301 GGSSGAYIPREVIEHTDNFVRSEDLEELGGTVSYVEIDEMTGQQQVVVCSSIEELEADAA 360
361 AEIITEDQVHEEVILSSNSSTESENEVNVNAIAKAYAEGCTSSAAMLQPILQAAIKATPK 420
421 VEVERIHEKIVKVKTEKHDLPSMQTAPHYQHSHRQNLETIVQAIRHLEGDHLFADGSGGQ 480
481 EKFGQQQNLQQHHHQMSGVHHQQLQHHRLAQDAPLALTTTGKQHAALAELRPFLQLKSGG 540
541 NKQVIITAKTAKDSGGLVSTSTSSTAVTPTAIFKVQTTGGHGNGSHLPAGSSTGTIITGS 600
601 NGSGGAQQLTITTSLKQCRPGVIVAKQLPSS
Interface Residues: 98, 100, 101, 102, 104, 105, 108, 109, 133
3D-footprint Homologues: 7z5k_B, 8osb_B, 2ypa_A, 1an4_A, 1am9_A, 7ssa_L, 6g1l_A, 7d8t_A, 7f2f_B, 5eyo_A, 2ql2_D
Binding Motifs: M4899_1.02 rTCAGCTGkty
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.