Transcription Factor
| Accessions: | UP00013A (UniPROBE 20160601), UP00408A (UniPROBE 20160601) |
| Names: | alpha, E4tf1a, GA repeat binding protein, GA-binding protein alpha chain, GABP-alpha subunit, Gabpa |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | Q00422 |
| Description: | GA repeat binding protein, alpha: Mus musculus GA repeat binding protein, alpha |
| Length: | 116 |
| Pfam Domains: | 16-98 Ets-domain |
| Sequence: (in bold interface residues) | 1 GEDRSSPGNRTGNNGQIQLWQFLLELLTDKDARDCISWVGDEGEFKLNQPELVAQKWGQR 60 61 KNKPTMNYEKLSRALRYYYDGDMICKVQGKRFVYKFVCDLKTLIGYSAAELNRLVI |
| Interface Residues: | 14, 69, 70, 72, 73, 74, 76, 77, 91 |
| 3D-footprint Homologues: | 3zp5_A, 4uno_A, 3jtg_A, 1dux_F, 7jsa_J, 8ee9_F, 4mhg_A, 2stt_A, 4iri_A, 1bc8_C, 4l18_B, 4lg0_B, 1yo5_C, 4bqa_A, 1awc_A |
| Binding Motifs: | UP00013A_1 mmawACCGGAAGTkhwv UP00408A_1 mvwtACCGGAAGTrkwr UP00013A_2 cydtywTccsmcysmh |
| Binding Sites: | AACCGGAA AACTTCCG ACATCCGG ACCGGAAA ACCGGATG ACTTCCGG ATTTCCGG CACCGGAA CACTTCCG CCGGAAAC CCGGAAGC CGGAAGTA CGGAAGTC CTTCCGGA CTTCCGGC GACCGGAA GCCGGAAA TACCGGAA TCCGGAAA TTCCGGAA |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] Wei G-H, Badis G, Berger MF, Kivioja T, Palin K, Enge M, Bonke M, Jolma A, Varjosalo M, Gehrke AR, Yan J, Talukder S, Turunen M, Taipale M, Stunnenberg HG, Ukkonen E, Hughes TR, Bulyk ML, Taipale J. Genome-wide analysis of ETS family DNA-binding in vitro and in vivo. The EMBO Journal. Epub 2010 Jun 1. doi:10.1038/emboj.2010.106 [Pubmed] |
| Related annotations: | PaperBLAST |
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