Transcription Factor
| Accessions: | O43829 (JASPAR 2024) |
| Names: | hZF5, ZBT14_HUMAN, ZF5, Zfp-161, Zfp-5, Zinc finger and BTB domain-containing protein 14, Zinc finger protein 161 homolog, Zinc finger protein 478, Zinc finger protein 5 homolog |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 449 |
| Pfam Domains: | 26-127 BTB/POZ domain 278-299 C2H2-type zinc finger 279-299 Zinc finger, C2H2 type 292-316 Zinc-finger double domain 305-325 Zinc-finger of C2H2 type 305-327 C2H2-type zinc finger 305-327 Zinc finger, C2H2 type 319-342 Zinc-finger double domain 333-355 Zinc finger, C2H2 type 333-353 Zinc-finger of C2H2 type 333-355 C2H2-type zinc finger 347-372 Zinc-finger double domain 361-383 Zinc finger, C2H2 type 361-381 Zinc-finger of C2H2 type 361-383 C2H2-type zinc finger 375-399 Zinc-finger double domain 389-412 Zinc finger, C2H2 type 389-412 C2H2-type zinc finger |
| Sequence: (in bold interface residues) | 1 MEFFISMSETIKYNDDDHKTLFLKTLNEQRLEGEFCDIAIVVEDVKFRAHRCVLAACSTY 60 61 FKKLFKKLEVDSSSVIEIDFLRSDIFEEVLNYMYTAKISVKKEDVNLMMSSGQILGIRFL 120 121 DKLCSQKRDVSSPDENNGQSKSKYCLKINRPIGDAADTQDDDVEEIGDQDDSPSDDTVEG 180 181 TPPSQEDGKSPTTTLRVQEAILKELGSEEVRKVNCYGQEVESMETPESKDLGSQTPQALT 240 241 FNDGMSEVKDEQTPGWTTAASDMKFEYLLYGHHREQIACQACGKTFSDEGRLRKHEKLHT 300 301 ADRPFVCEMCTKGFTTQAHLKEHLKIHTGYKPYSCEVCGKSFIRAPDLKKHERVHSNERP 360 361 FACHMCDKAFKHKSHLKDHERRHRGEKPFVCGSCTKAFAKASDLKRHENNMHSERKQVTP 420 421 SAIQSETEQLQAAAMAAEAEQQLETIACS |
| Interface Residues: | 287, 288, 289, 290, 291, 294, 298, 305, 315, 316, 317, 318, 319, 321, 322, 324, 325, 326, 328, 343, 344, 345, 346, 347, 349, 350, 353, 354, 371, 372, 373, 374, 375, 378, 400, 401, 402, 403, 405, 406 |
| 3D-footprint Homologues: | 5v3j_F, 8cuc_F, 7y3l_A, 1tf3_A, 7n5w_A, 1tf6_A, 8ssq_A, 7w1m_H, 6u9q_A, 8ssu_A, 8h9h_G, 7y3m_I, 2kmk_A, 7txc_E, 8gn3_A, 2gli_A, 7ysf_A, 6e94_A, 2jpa_A, 1ubd_C, 2lt7_A, 2drp_D |
| Binding Motifs: | MA1650.1 ssCCGCGCACss MA1650.2 CCGCGCAC |
| Binding Sites: | MA1650.2.4 MA1650.2.11 MA1650.2.3 MA1650.1.1 MA1650.1.10 / MA1650.1.9 MA1650.1.10 / MA1650.1.11 MA1650.1.11 / MA1650.1.12 MA1650.1.12 / MA1650.1.13 MA1650.1.13 / MA1650.1.14 MA1650.1.14 / MA1650.1.15 MA1650.1.15 / MA1650.1.16 MA1650.1.16 / MA1650.1.17 MA1650.1.17 / MA1650.1.18 MA1650.1.18 / MA1650.1.19 MA1650.1.2 MA1650.1.20 MA1650.1.3 MA1650.1.4 MA1650.1.5 MA1650.1.5 / MA1650.1.6 MA1650.1.6 / MA1650.1.7 MA1650.1.7 / MA1650.1.8 MA1650.1.8 / MA1650.1.9 MA1650.1.19 MA1650.1.20 MA1650.2.1 / MA1650.2.7 MA1650.2.10 / MA1650.2.14 / MA1650.2.18 MA1650.2.12 / MA1650.2.13 / MA1650.2.2 / MA1650.2.8 MA1650.2.15 / MA1650.2.17 / MA1650.2.5 MA1650.2.16 / MA1650.2.20 / MA1650.2.9 MA1650.2.19 MA1650.2.6 |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.