Transcription Factor

						

			
Accessions: Q8TAW3 (JASPAR 2024)

			
Names: ZN671_HUMAN
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q8TAW3
Length: 534
Pfam Domains:     49-89 KRAB box
  192-201 C2H2-type zinc finger
  284-296 C2H2-type zinc finger
  285-307 Zinc finger, C2H2 type
  285-307 C2H2-type zinc finger
  300-323 Zinc-finger double domain
  312-329 C2H2-type zinc finger
  313-335 Zinc finger, C2H2 type
  313-335 C2H2-type zinc finger
  328-351 Zinc-finger double domain
  340-363 C2H2-type zinc finger
  341-363 Zinc finger, C2H2 type
  341-363 C2H2-type zinc finger
  356-380 Zinc-finger double domain
  368-391 C2H2-type zinc finger
  369-391 Zinc finger, C2H2 type
  369-391 C2H2-type zinc finger
  369-391 C2H2-type zinc-finger domain
  383-407 Zinc-finger double domain
  397-419 Zinc finger, C2H2 type
  397-419 C2H2-type zinc finger
  397-408 C2H2-type zinc finger
  412-435 Zinc-finger double domain
  424-435 C2H2-type zinc finger
  425-447 Zinc finger, C2H2 type
  425-447 C2H2-type zinc finger
  451-473 C2H2-type zinc finger
  451-474 C2H2-type zinc finger
  468-490 Zinc-finger double domain
  478-497 C2H2-type zinc finger
  479-501 Zinc finger, C2H2 type
  479-501 C2H2-type zinc finger
  493-516 Zinc-finger double domain
  507-519 C2H2-type zinc finger
  507-529 Zinc finger, C2H2 type
  507-529 C2H2-type zinc finger
Sequence: 
(in bold interface residues)		   1 MLSPVSRDASDALQGRKCLRPRSRRLPLPAAVRAHGPMAELTDSARGCVVFEDVFVYFSR   60
  61 EEWELLDDAQRLLYHDVMLENFALLASLGIAFSRSRAVMKLERGEEPWVYDQVDMTSATE  120
 121 REAQRGLRPGCWHGVEDEEVSSEQSIFVAGVSEVRTLMAELESHPCDICGPILKDTLHLA  180
 181 KYHGGKARQKPYLCGACGKQFWFSTDFDQHQNQPNGGKLFPRKEGRDSVKSCRVHVPEKT  240
 241 LTCGKGRRDFSATSGLLQHQASLSSMKPHKSTKLVSGFLMGQRYHRCGECGKAFTRKDTL  300
 301 ARHQRIHTGERPYECNECGKFFSQSYDLFKHQTVHTGERPYECSECGKFFRQISGLIEHR  360
 361 RVHTGERLYQCGKCGKFFSSKSNLIRHQEVHTGARPYVCSECGKEFSRKHTLVLHQRTHT  420
 421 GERPYECSECGKAFSQSSHLNVHWRIHSSDYECSRCGKAFSCISKLIQHQKVHSGEKPYE  480
 481 CSKCGKAFTQRPNLIRHWKVHTGERPYVCSECGREFIRKQTLVLHQRVHAGEKL
Interface Residues: 295, 296, 297, 298, 299, 302, 323, 324, 326, 327, 330, 334, 351, 352, 353, 354, 355, 356, 357, 358, 359, 360, 361, 362, 364, 379, 380, 381, 382, 383, 384, 386, 387, 390, 407, 408, 409, 410, 411, 413, 414, 435, 436, 437, 438, 439, 441, 442, 445, 446, 462, 463, 464, 465, 467, 468, 474, 477, 488, 490, 491, 492, 493, 494, 495, 496, 500, 517, 518, 519, 520, 521
3D-footprint Homologues: 6jnm_A, 7w1m_H, 2i13_A, 8gn3_A, 2kmk_A, 7ysf_A, 6a57_A, 1tf3_A, 8ssq_A, 1tf6_A, 5kkq_D, 8ssu_A, 5ei9_F, 6wmi_A, 6ml4_A, 5v3j_F, 5und_A, 4m9v_C, 7eyi_G, 6e94_A, 5yel_A, 2jpa_A, 1ubd_C, 7n5w_A, 4x9j_A, 6blw_A, 1mey_C, 5kl3_A, 1g2f_F, 8h9h_G, 8cuc_F, 7y3l_A, 3uk3_C, 1llm_D, 6u9q_A, 1f2i_J, 5k5i_A, 2gli_A, 7y3m_I, 5k5l_F, 5yj3_D, 2lt7_A, 7vru_C, 2wbs_A, 7txc_E, 2drp_D
Binding Motifs: UN0336.1 rkkGAGTGGAGyrrr
UN0336.2 GAGTGGAG
Binding Sites: UN0336.2.14 / UN0336.2.18 / UN0336.2.20
UN0336.1.1
UN0336.1.10
UN0336.1.11 / UN0336.1.7
UN0336.1.12 / UN0336.1.8
UN0336.1.13 / UN0336.1.9
UN0336.1.10 / UN0336.1.14
UN0336.1.11 / UN0336.1.15
UN0336.1.12 / UN0336.1.16
UN0336.1.13 / UN0336.1.17
UN0336.1.18
UN0336.1.15 / UN0336.1.19
UN0336.1.2
UN0336.1.20
UN0336.1.3
UN0336.1.4
UN0336.1.5
UN0336.1.6
UN0336.1.7
UN0336.1.8
UN0336.1.9
UN0336.1.14
UN0336.1.16
UN0336.1.17
UN0336.1.18
UN0336.1.19
UN0336.1.20
UN0336.2.1 / UN0336.2.12 / UN0336.2.9
UN0336.2.10 / UN0336.2.4
UN0336.2.11
UN0336.2.13
UN0336.2.15 / UN0336.2.19 / UN0336.2.7 / UN0336.2.8
UN0336.2.16 / UN0336.2.17 / UN0336.2.3
UN0336.2.2 / UN0336.2.5
UN0336.2.6
			
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.