Transcription Factor

						

			
Accessions: 6pax_A (3D-footprint 20231221)

			
Names: Aniridia type II protein, HOMEOBOX PROTEIN PAX-6, Oculorhombin, Paired box protein Pax-6, PAX6_HUMAN
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P26367
Length: 133
Pfam Domains:     1-125 'Paired box' domain
Sequence: 
(in bold interface residues)		   1 SHSGVNQLGGVFVNGRPLPDSTRQRIVELAHSGARPCDISRILQVSNGCVSKILGRYYAT   60
  61 GSIRPRAIGGSKPRVATPEVVSKIAQYKQECPSIFAWEIRDRLLSEGVCTNDNIPSVSSI  120
 121 NRVLRNLASEKQQ
Interface Residues: 14, 46, 47, 49, 51, 52, 68, 71, 74, 116, 117, 118, 119, 121, 122, 125
3D-footprint Homologues: 1pdn_C, 6pax_A, 1k78_A
Binding Motifs: 6pax_A ACGcAnnCGTGC
Binding Sites: 6pax_B
6pax_C
			
Publications: Xu H.E, Rould M.A, Xu W, Epstein J.A, Maas R.L, Pabo C.O. Crystal structure of the human Pax6 paired domain-DNA complex reveals specific roles for the linker region and carboxy-terminal subdomain in DNA binding. Genes & development 13:1263-75 (1999). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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