Transcription Factor
| Accessions: | P22813 (JASPAR 2024) |
| Names: | Heat shock factor protein, Heat shock transcription factor, HSF_DROME, HSTF |
| Organisms: | Drosophila melanogaster |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 691 |
| Pfam Domains: | 48-151 HSF-type DNA-binding |
| Sequence: (in bold interface residues) | 1 MSRSRSSAKAVQFKHESEEEEEDEEEQLPSRRMHSYGDAAAIGSGVPAFLAKLWRLVDDA 60 61 DTNRLICWTKDGQSFVIQNQAQFAKELLPLNYKHNNMASFIRQLNMYGFHKITSIDNGGL 120 121 RFDRDEIEFSHPFFKRNSPFLLDQIKRKISNNKNGDDKGVLKPEAMSKILTDVKVMRGRQ 180 181 DNLDSRFSAMKQENEVLWREIASLRQKHAKQQQIVNKLIQFLITIVQPSRNMSGVKRHVQ 240 241 LMINNTPEIDRARTTSETESESGGGPVIHELREELLDEVMNPSPAGYTAASHYDQESVSP 300 301 PAVERPRSNMSISSHNVDYSNQSVEDLLLQGNGTAGGNILVGGAASPMAQSVSQSPAQHD 360 361 VYTVTEAPDSHVQEVPNSPPYYEEQNVLTTPMVREQEQQKRQQLKENNKLRRQAGDVILD 420 421 AGDILVDSSSPKAQRTSIQHSTQPDVMVQPMIIKSEPENSSGLMDLMTPANDLYSVNFIS 480 481 EDMPTDIFEDALLPDGVEEAAKLDQQQKFGQSTVSSGKFASNFDVPTNSTLLDANQASTS 540 541 KAAAKAQASEEEGMAVAKYSGAENGNNRDTNNSQLLRMASVDELHGHLESMQDELETLKD 600 601 LLRGDGVAIDQNMLMGLFNDSDLMDNYGLSFPNDSISSEKKAPSGSELISYQPMYDLSDI 660 661 LDTDDGNNDQEASRRQMQTQSSVLNTPRHEL |
| Interface Residues: | 93, 94, 99, 101, 102, 103, 105, 106, 147 |
| 3D-footprint Homologues: | 5hdn_C, 5d5w_B, 3hts_B, 5d5v_B, 7dci_A |
| Binding Motifs: | MA1458.1 wwTTCcAGAAww MA1458.2 TTCcAGAA |
| Binding Sites: | MA1458.2.19 / MA1458.2.20 / MA1458.2.8 / MA1458.2.9 MA1458.2.11 / MA1458.2.14 / MA1458.2.17 / MA1458.2.4 / MA1458.2.5 / MA1458.2.7 MA1458.1.1 MA1458.1.10 / MA1458.1.9 MA1458.1.10 / MA1458.1.11 MA1458.1.12 MA1458.1.11 / MA1458.1.13 MA1458.1.12 / MA1458.1.14 MA1458.1.13 / MA1458.1.15 MA1458.1.14 / MA1458.1.16 MA1458.1.16 / MA1458.1.17 MA1458.1.17 / MA1458.1.18 MA1458.1.18 / MA1458.1.19 MA1458.1.2 MA1458.1.19 / MA1458.1.20 MA1458.1.3 MA1458.1.4 MA1458.1.5 MA1458.1.6 MA1458.1.7 MA1458.1.7 / MA1458.1.8 MA1458.1.8 / MA1458.1.9 MA1458.1.15 MA1458.1.20 MA1458.2.1 MA1458.2.10 MA1458.2.12 MA1458.2.13 / MA1458.2.3 MA1458.2.15 MA1458.2.16 MA1458.2.18 / MA1458.2.2 MA1458.2.6 |
| Publications: | Nitta KR, Jolma A, Yin Y, Morgunova E, Kivioja T, Akhtar J, Hens K, Toivonen J, Deplancke B, Furlong EE, Taipale J. Conservation of transcription factor binding specificities across 600 million years of bilateria evolution. Elife : (2015). [Pubmed] |
| Related annotations: | PaperBLAST |
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