Transcription Factor

						

			
Accessions: T015242_1.02 (CISBP 1.02), USF2_MOUSE (HOCOMOCO 10)

			
Names: T015242_1.02;, Usf2, Major late transcription factor 2, Upstream stimulatory factor 2, Upstream transcription factor 2, USF2_MOUSE
Organisms: Rattus norvegicus, Mus musculus
Libraries: CISBP 1.02 1, HOCOMOCO 10 2
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]

2 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed]
Notes: experiment type:PBM, family:bHLH
Length: 346
Pfam Domains:   236-290 Helix-loop-helix DNA-binding domain
Sequence: 
(in bold interface residues)		   1 MDMLDPGLDPASSATAAAAASHDKGPEAEEGVELQEGGDGPGAEEQTAVAIASVQQAAFG   60
  61 DHNIQYQFRTESNGGQVTYRVVQVTDGQLDGQGDAAGAVSVVSTAAFAGGQQAVTQVGVD  120
 121 GAAQRPGPAAASVPTGPAAPFPLAVIQNPFSNGGSPAAEAVSGEARFAYFPASSVGDTTA  180
 181 VSVQTTDQSLQAGGQFYVMMTPQDVLQTGTQRTIAPRTHPYSPKIDGTRTPRDERRRAQH  240
 241 NEVERRRRDKINNWIVQLSKIIPDCHADNSKTGASKGGILSKACDYIRELRQTNQRMQET  300
 301 FKEAERLQMDNELLRQQIEELKNENALLRAQLQQHNLEMVGESTRQ
Interface Residues: 237, 239, 240, 241, 243, 244, 247, 248, 252, 274, 276
3D-footprint Homologues: 1a0a_B, 1an4_A, 1am9_A, 7f2f_B, 5eyo_A, 7xi3_A, 5v0l_A, 7rcu_E, 5gnj_I, 6g1l_A, 4h10_A, 7ssa_L, 5i50_B, 7xq5_A, 7d8t_A, 4zpk_A, 5nj8_D, 8osl_P, 7xhv_B, 7xi3_B
Binding Motifs: M0225_1.02 rTCACGTGkk
USF2_MOUSE.H10MO.A|M01406 gGTCACGTGryss
			
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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