Transcription Factor

Accessions: T078273_1.02 (CISBP 1.02), ELK1_MOUSE (HOCOMOCO 10)
Names: Elk1, T078273_1.02;, ELK1_MOUSE
Organisms: Mus musculus
Libraries: CISBP 1.02 1, HOCOMOCO 10 2
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
2 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed]
Notes: experiment type:PBM, family:Ets
Length: 429
Pfam Domains: 5-87 Ets-domain
Sequence:
(in bold interface residues)
1 MDPSVTLWQFLLQLLREQGNGHIISWTSRDGGEFKLVDAEEVARLWGLRKNKTNMNYDKL 60
61 SRALRYYYDKNIIRKVSGQKFVYKFVSYPEVAGCSTEDCPPQPEVSVTSAIAMAPATVHA 120
121 GPGDTATGKPGTPKGAGMTGQGGLARSSRNEYMRSGLYSTFTIQSLQPQPQPPIPPRPAS 180
181 VLPNTTPAGVPAPASGSRSTSPNPLEACLEAEEAGLPLQVILTPPEAPNQKSEELSLDPS 240
241 FGHPQPPEVKVEGPKEELEAARAGGFSSEAVKAEPEVSASEGLLARLPAILTENTAQVCG 300
301 LSTSTTEITQPQKGRKPRDLELPLSPSLLGGQGPERTPGSGTSSGLQAPGPALTPSLLPT 360
361 HTLTPVLLTPSSLPPSIHFWSTLSPIAPRSPAKLSFQFPSSGSAQVHIPSISVDGLSTPV 420
421 VLSPGPQKP
Interface Residues: 58, 59, 61, 62, 63, 65, 66, 80
3D-footprint Homologues: 8ee9_F, 4mhg_A, 2stt_A, 4uno_A, 3jtg_A, 1dux_F, 7jsa_J, 3zp5_A, 4bqa_A, 1awc_A, 4iri_A, 1bc8_C, 4l18_B, 4lg0_B, 1yo5_C
Binding Motifs: M0695_1.02 rrCCGGAAgy
ELK1_MOUSE.H10MO.B|M01070 rCCGGAArt
Related annotations: PaperBLAST

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