Transcription Factor
Accessions: | 1g2d_F (3D-footprint 20231221) |
Names: | Early growth response protein 1, EGR-1, EGR1_MOUSE, Nerve growth factor-induced protein A, NGFI-A, TATA BOX ZINC FINGER PROTEIN, Transcription factor Zif268, Zinc finger protein Krox-24 |
Organisms: | Mus musculus |
Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
Uniprot: | P08046 |
Length: | 88 |
Pfam Domains: | 5-29 C2H2-type zinc finger 5-29 Zinc finger, C2H2 type 21-45 Zinc-finger double domain 35-57 C2H2-type zinc finger 35-57 Zinc finger, C2H2 type 50-74 Zinc-finger double domain 63-81 C2H2-type zinc finger |
Sequence: (in bold interface residues) | 1 MERPYACPVESCDRRFSQKTNLDTHIRIHTGQKPFQCRICMRNFSQHTGLNQHIRTHTGE 60 61 KPFACDICGRKFATLHTRDRHTKIHLRQ |
Interface Residues: | 17, 18, 19, 20, 21, 23, 24, 45, 46, 47, 48, 49, 51, 52, 53, 63, 73, 74, 75, 76, 77, 78, 79, 80, 81 |
3D-footprint Homologues: | 6ml4_A, 7n5w_A, 3uk3_C, 1tf3_A, 6jnm_A, 5und_A, 4x9j_A, 2i13_A, 5k5l_F, 8ssu_A, 1ubd_C, 5ei9_F, 2jpa_A, 1mey_C, 6blw_A, 5kkq_D, 1f2i_J, 6u9q_A, 2kmk_A, 5kl3_A, 2gli_A, 7ysf_A, 1g2f_F, 6wmi_A, 8ssq_A, 1tf6_A, 7w1m_H, 7eyi_G, 5v3j_F, 8h9h_G, 6e94_A, 2lt7_A, 6a57_A, 8cuc_F, 7y3l_A, 1llm_D, 2wbs_A, 2drp_D, 5yel_A, 7txc_E, 5k5i_A, 4m9v_C, 7y3m_I, 8gn3_A, 5hso_A, 5yj3_D |
Binding Motifs: | 1g2d_F CGCTATAAAAm |
Binding Sites: | 1g2d_D 1g2d_E |
Publications: | Wolfe S.A, Grant R.A, Elrod-Erickson M, Pabo C.O. Beyond the "recognition code": structures of two Cys2His2 zinc finger/TATA box complexes. Structure (London, England : 1993) 9:717-23 (2001). [Pubmed] |
Related annotations: | PaperBLAST |
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