Transcription Factor
| Accessions: | VDR_MOUSE (HOCOMOCO 10), P48281 (JASPAR 2024) |
| Names: | 1,25-dihydroxyvitamin D3 receptor, Nuclear receptor subfamily 1 group I member 1, VDR_MOUSE, Vitamin D3 receptor |
| Organisms: | Mus musculus |
| Libraries: | HOCOMOCO 10 1, JASPAR 2024 2 1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | P48281 |
| Length: | 422 |
| Pfam Domains: | 23-91 Zinc finger, C4 type (two domains) 220-410 Ligand-binding domain of nuclear hormone receptor |
| Sequence: (in bold interface residues) | 1 MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTC 60 61 PFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMIMKRKEEEALKDSL 120 121 RPKLSEEQQHIIAILLDAHHKTYDPTYADFRDFRPPIRADVSTGSYSPRPTLSFSGDSSS 180 181 NSDLYTPSLDMMEPASFSTMDLNEEGSDDPSVTLDLSPLSMLPHLADLVSYSIQKVIGFA 240 241 KMIPGFRDLTSDDQIVLLKSSAIEVIMLRSNQSFTLDDMSWDCGSQDYKYDITDVSRAGH 300 301 TLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAKLVEAIQDRLSNTLQT 360 361 YIRCRHPPPGSHQLYAKMIQKLADLRSLNEEHSKQYRSLSFQPENSMKLTPLVLEVFGNE 420 421 IS |
| Interface Residues: | 32, 33, 35, 36, 42, 43, 45, 46, 49, 50, 74, 100, 103, 104, 105 |
| 3D-footprint Homologues: | 6fbq_A, 6l6q_B, 7wnh_D, 1a6y_A, 1lo1_A, 3g9m_B, 4oln_B, 2a66_A, 2nll_B, 1lat_A, 7xv6_B, 2ff0_A, 1dsz_A, 4umm_E, 3cbb_A, 8cef_H, 4iqr_B, 2han_A, 1hcq_E, 8hbm_B, 5krb_G, 2han_B, 1kb2_B, 4tnt_B, 5e69_A, 4hn5_B, 5emc_A, 7prw_B, 5cbx_B, 3g6t_A, 1r4i_A, 5cbz_E |
| Binding Motifs: | MA0693.1 GrGTTCAyyGrGTTCA VDR_MOUSE.H10MO.C|M01407 rGGTCAwsrrGkTCac MA0693.3 ywgAGTTCAtw MA0693.4 gAGTTCA |
| Binding Sites: | MA0693.3.1 MA0693.3.10 / MA0693.3.13 MA0693.3.11 MA0693.3.12 / MA0693.3.14 MA0693.3.13 / MA0693.3.15 MA0693.3.14 / MA0693.3.17 MA0693.3.15 / MA0693.3.18 MA0693.3.16 / MA0693.3.19 MA0693.3.17 / MA0693.3.20 MA0693.3.18 MA0693.3.19 MA0693.3.2 MA0693.3.20 MA0693.3.3 MA0693.3.4 MA0693.3.5 MA0693.3.6 MA0693.3.7 / MA0693.3.8 MA0693.3.11 / MA0693.3.8 MA0693.3.12 / MA0693.3.9 MA0693.3.16 MA0693.3.10 MA0693.3.6 MA0693.3.7 MA0693.3.9 MA0693.4.1 / MA0693.4.15 / MA0693.4.18 MA0693.4.10 / MA0693.4.4 / MA0693.4.9 MA0693.4.11 MA0693.4.12 MA0693.4.13 / MA0693.4.14 / MA0693.4.5 MA0693.4.16 / MA0693.4.8 MA0693.4.17 MA0693.4.19 MA0693.4.2 MA0693.4.20 MA0693.4.3 MA0693.4.6 MA0693.4.7 |
| Publications: | Nishikawa J, Kitaura M, Matsumoto M, Imagawa M, Nishihara T. Difference and similarity of DNA sequence recognized by VDR homodimer and VDR/RXR heterodimer. Nucleic Acids Res 22:2902-7 (1994). [Pubmed] |
| Related annotations: | PaperBLAST |
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