Transcription Factor
| Accessions: | TCF4_DBD (HumanTF 1.0) |
| Names: | Beta-catenin-interacting protein 1, CNBP1_HUMAN, Inhibitor of beta-catenin and Tcf-4, TCF4 |
| Organisms: | Homo sapiens |
| Libraries: | HumanTF 1.0 1 1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] |
| Uniprot: | Q9NSA3 |
| Notes: | Ensembl ID: ENSG00000196628; DNA-binding domain sequence; TF family: bHLH; Clone source: MGC |
| Length: | 131 |
| Pfam Domains: | 34-87 Helix-loop-helix DNA-binding domain |
| Sequence: (in bold interface residues) | 1 MALDDDKKDIKSITSNNDDEDLTPEQKAEREKERRMANNARERLRVRDINEAFKELGRMV 60 61 QLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSSEPPPLSLA 120 121 GPHPGMGDASN |
| Interface Residues: | 35, 38, 39, 41, 42, 43, 45, 46 |
| 3D-footprint Homologues: | 2ypa_A, 7z5k_B, 6g1l_A, 6od3_F, 2ql2_D, 2ypa_B, 2ql2_A |
| Binding Motifs: | TCF4_DBD yrCACCTGbw |
| Publications: | Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] |
| Related annotations: | PaperBLAST |
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