Transcription Factor
| Accessions: | Q5HY98 (JASPAR 2024) |
| Names: | ZN766_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q5HY98 |
| Length: | 468 |
| Pfam Domains: | 9-49 KRAB box 230-253 Zinc-finger double domain 242-255 C2H2-type zinc finger 243-265 Zinc finger, C2H2 type 243-265 C2H2-type zinc finger 258-282 Zinc-finger double domain 270-291 C2H2-type zinc finger 271-293 Zinc finger, C2H2 type 271-293 C2H2-type zinc finger 286-309 Zinc-finger double domain 298-311 C2H2-type zinc finger 299-321 Zinc finger, C2H2 type 299-321 C2H2-type zinc finger 314-337 Zinc-finger double domain 326-345 C2H2-type zinc finger 327-349 Zinc finger, C2H2 type 327-349 C2H2-type zinc finger 341-366 Zinc-finger double domain 354-378 C2H2-type zinc finger 355-377 Zinc finger, C2H2 type 355-378 C2H2-type zinc finger 369-394 Zinc-finger double domain 382-393 C2H2-type zinc finger 383-405 C2H2-type zinc finger 383-405 Zinc finger, C2H2 type 397-422 Zinc-finger double domain 410-423 C2H2-type zinc finger 411-433 Zinc finger, C2H2 type 411-433 C2H2-type zinc finger 425-450 Zinc-finger double domain 438-461 C2H2-type zinc finger 439-462 Zinc finger, C2H2 type 439-462 C2H2-type zinc finger |
| Sequence: (in bold interface residues) | 1 MAQLRRGHLTFRDVAIEFSQEEWKCLDPVQKALYRDVMLENYRNLVSLGICLPDLSIISM 60 61 MKQRTEPWTVENEMKVAKNPDRWEGIKDINTGRSCAVRSKAGNKPITNQLGLTFQLPLPE 120 121 LEIFQGEGKIYECNQVQKFISHSSSVSPLQRIYSGVKTHIFNKHRNDFVDFPLLSQEQKA 180 181 HIRRKPYECNEQGKVFRVSSSLPNHQVIHTADKPNRCHECGKTVRDKSGLAEHWRIRTGE 240 241 KPYKCKECGKLFNRIAYLARHEKVHTGESPYKCNECGKVFSRITYLVRHQKIHTREKPHK 300 301 CNKCGKVYSSSSYLAQHWRIHTGEKLYKCNKCGKEFSGHSSLTTHLLIHTGEKPYKCKEC 360 361 DKAFRHKFSLTVHQRNHNGEKPYKCHECGKVFTQVSHLARHQKIHTGEKPYKCNECGKVF 420 421 TQNSHLANHQRIHTGEKPYKCHVCGKVFRHSSWFVQHQRSVHERVLTN |
| Interface Residues: | 200, 204, 225, 227, 228, 229, 232, 233, 254, 255, 256, 257, 258, 260, 261, 264, 282, 283, 284, 285, 288, 309, 310, 311, 312, 313, 316, 320, 337, 338, 340, 341, 344, 355, 365, 366, 367, 368, 369, 371, 372, 374, 375, 378, 393, 394, 395, 396, 397, 399, 400, 406, 420, 421, 422, 423, 424, 425, 428, 431, 432, 449, 450, 451, 452, 453, 454, 455, 456 |
| 3D-footprint Homologues: | 7w1m_H, 4m9v_C, 8ssq_A, 6blw_A, 8ssu_A, 5v3j_F, 8cuc_F, 5kkq_D, 1tf6_A, 8h9h_G, 7y3m_I, 6jnm_A, 3uk3_C, 5k5l_F, 2wbs_A, 1g2f_F, 6ml4_A, 5yel_A, 6a57_A, 2kmk_A, 1tf3_A, 7n5w_A, 6u9q_A, 2gli_A, 5ei9_F, 5k5i_A, 6e94_A, 7ysf_A, 2jpa_A, 1ubd_C, 7y3l_A, 2drp_D, 4x9j_A, 1f2i_J, 8gn3_A, 5kl3_A, 7txc_E, 2lt7_A, 5yj3_D, 1llm_D |
| Binding Motifs: | UN0223.1 maAAkAAACCtc MA2098.1 AAkAAACCt |
| Binding Sites: | UN0223.1.1 UN0223.1.10 / UN0223.1.11 / UN0223.1.12 UN0223.1.13 UN0223.1.14 UN0223.1.15 / UN0223.1.16 UN0223.1.16 / UN0223.1.17 / UN0223.1.18 UN0223.1.18 / UN0223.1.19 UN0223.1.19 / UN0223.1.20 UN0223.1.1 / UN0223.1.2 / UN0223.1.3 / UN0223.1.4 UN0223.1.20 UN0223.1.4 / UN0223.1.5 / UN0223.1.6 / UN0223.1.7 UN0223.1.5 / UN0223.1.6 / UN0223.1.7 / UN0223.1.8 / UN0223.1.9 UN0223.1.15 UN0223.1.9 MA2098.1.1 / MA2098.1.2 / MA2098.1.3 MA2098.1.10 / MA2098.1.11 / MA2098.1.12 MA2098.1.13 / MA2098.1.16 MA2098.1.14 MA2098.1.15 MA2098.1.17 / MA2098.1.18 MA2098.1.19 / MA2098.1.4 / MA2098.1.5 / MA2098.1.6 / MA2098.1.7 / MA2098.1.8 MA2098.1.20 MA2098.1.9 |
| Publications: | ENCODE Project Consortium. An integrated encyclopedia of DNA elements in the human genome. Nature 489:57-74 (2012). [Pubmed] |
| Related annotations: | PaperBLAST |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.