Transcription Factor

						

			
Accessions: UP00002A (UniPROBE 20160601)

			
Names: 5730497N03Rik, HF-1b, HF1-b, Sp4, trans-acting transcription factor 4, Transcription factor Sp4
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: Q62445
Description: trans-acting transcription factor 4: Mus musculus similar to trans-acting transcription factor 4 (LOC211769), mRNA
Length: 113
Pfam Domains:     16-40 C2H2-type zinc finger
    16-40 Zinc finger, C2H2 type
    32-59 Zinc-finger double domain
    46-70 C2H2-type zinc finger
    46-70 Zinc finger, C2H2 type
    63-85 Zinc-finger double domain
    76-98 C2H2-type zinc finger
    76-98 Zinc finger, C2H2 type
Sequence: 
(in bold interface residues)		   1 EGEGRGSSEPGKKKQHVCHIEGCGKVYGKTSHLRAHLRWHTGERPFICNWMFCGKRFTRS   60
  61 DELQRHRRTHTGEKRFECPECSKRFMRSDHLSKHVKTHQNKKGGGTALAIVTS
Interface Residues: 28, 29, 30, 31, 32, 34, 35, 37, 38, 41, 58, 59, 60, 61, 62, 64, 65, 66, 69, 86, 87, 88, 89, 90, 91, 92, 93, 94, 97
3D-footprint Homologues: 6jnm_A, 8cuc_F, 1tf3_A, 7y3l_A, 6ml4_A, 7n5w_A, 2i13_A, 1llm_D, 5kl3_A, 1ubd_C, 7ysf_A, 5ei9_F, 8ssq_A, 1mey_C, 7w1m_H, 5und_A, 7eyi_G, 5k5i_A, 2kmk_A, 8ssu_A, 2gli_A, 8gn3_A, 1g2f_F, 6blw_A, 5kkq_D, 1tf6_A, 6u9q_A, 5yel_A, 4x9j_A, 8h9h_G, 6e94_A, 6wmi_A, 2lt7_A, 7y3m_I, 6a57_A, 2jpa_A, 3uk3_C, 7txc_E, 2wbs_A, 2drp_D, 1f2i_J, 4m9v_C, 5yj3_D, 5v3j_F
Binding Motifs: UP00002A_1 kgymmCGCCCCCyysyc
UP00002A_2 ywwAGGCGTGkCyhd
Binding Sites: CCCGCCCC
AACGCCCC
ACCGCCCC
ACGCCCAC
ACGCCCAT
ACGCCCCC
ACGCCCCT
AGGGGCGG
AGGGGGCG
CACGCCCA
CACGCCCC
CCACGCCC
CCCCGCCC
CCCGCCCA
CCGCCCAC
CGCCCACC
CGCCCCCA
CGCCCCCC
GGGGCGTA
AGTGGGCG
			
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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