Transcription Factor

						

			
Accessions: Q4H2S2 (JASPAR 2024)

			
Names: HMG transcription factor SoxB2, Q4H2S2_CIOIN, Transcription factor protein
Organisms: Ciona intestinalis
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q4H2S2
Length: 318
Pfam Domains:     30-98 HMG (high mobility group) box
    31-90 Domain of unknown function (DUF1898)
Sequence: 
(in bold interface residues)		   1 MESPDLQRETPSPVTSEEMTLKSGIDTGHVKRPMNAFMVWSRGQRRKMAQENPKMHNSEI   60
  61 SKRLGASWKLLNECEKRPFIDEAKRLRALHMKEHPDYKYRPRRKPKSLIKPKDRFAFPLF  120
 121 PSSGMSSPTHDASTVSLAIQQAAAAAHLNMDPIVVEKARAAAAAAFYSTSQSLTTTSFPS  180
 181 LNPLSMTSQSNAVSLAAAITQSRLAAVAAARDLGTPNSMYSPSNGLYSPPATTGASRCGS  240
 241 LLHSPPSPGAAAMAAAVMNSAYVMNTPGAGSWSPSLPSPTLSMQNPFAYILVPGSSPFPA  300
 301 SPLKSGLDYFSPLPLPAM
Interface Residues: 32, 35, 37, 38, 39, 41, 45, 56, 57, 58, 61, 99, 101, 103, 106
3D-footprint Homologues: 2gzk_A, 4s2q_D, 1j5n_A, 2lef_A, 4y60_C, 1o4x_B, 3f27_D, 6jrp_D, 1qrv_A, 3u2b_C, 7m5w_A, 1hry_A, 1ckt_A
Binding Motifs: MA1916.1 wwwwkyyATTGTTttytttw
MA1916.2 ATTGTT
			
Publications: Chen WC, Pauls S, Bacha J, Elgar G, Loose M, Shimeld SM. Dissection of a Ciona regulatory element reveals complexity of cross-species enhancer activity. Dev Biol 390:261-72 (2014). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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