Transcription Factor
| Accessions: | T120854_1.02 (CISBP 1.02), UP00328A (UniPROBE 20160601), P34219 (JASPAR 2024) |
| Names: | T120854_1.02;, TOD6, Hypothetical 59.2 kDa protein in PTC3-SAS3 intergenic region, Pbf1, YBL0509, YBL0513, PAC-binding factor 1, TOD6_YEAST, Transcriptional regulatory protein TOD6, Twin of DOT6 |
| Organisms: | Saccharomyces cerevisiae |
| Libraries: | CISBP 1.02 1, UniPROBE 20160601 2, JASPAR 2024 3 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 2 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] 3 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Description: | Myb domain-containing protein YBL054W |
| Notes: | experiment type:PBM, family:Myb/SANT |
| Length: | 525 |
| Pfam Domains: | 77-120 Myb-like DNA-binding domain 78-121 Myb-like DNA-binding domain |
| Sequence: (in bold interface residues) | 1 MTLPKLSSVSVSSGHVSANSHGFSILSKHPHPNNLVHSHSLSHTNAKSHLPISSTSTKEN 60 61 STNKEEAESLKKNNPSSWDPSDDIKLRHLKEIKNLGWKEIAHHFPNRTPNACQFRWRRLK 120 121 SGNLKSNKTAVIDINKLFGVYATGDATPSAGTPSAEEAVKEEAVEDEDITAGSSAIEDSP 180 181 PDFKPLVKPKYMDRKLITQRSTSTFSDHEPQHTKPRKLFVKPRSFSHSITTNTPNVKTAQ 240 241 QTNLSLYNTTSAKTNKAVNSNDYENIGLVPKIIIRSRRNSFIPSTQIPHSTTKTRKNSHS 300 301 VISSRRSSFNMMHSRRSSFNSHAPTEPISRRASLVVSPYMSPRRLSTSQSVHYHPQHQYY 360 361 LNPIASPNCKTDHANDKITHTRTFLDMQKFANKHPWSREDDEVLLNNTKDKQNHLSPLEI 420 421 SIVLPNNRSELEIQQRMDYLKRKGRVSGFHTNEGCKDEEEEDDIDPLHKENGINTPSQQS 480 481 QNYGMLEAKHDNPKSSELSSMTSANDIRNEQDELPGINSIFKNIF |
| Interface Residues: | 75, 110, 111, 113, 114, 117, 119, 160 |
| 3D-footprint Homologues: | 3osg_A, 3zqc_A, 1ign_A |
| Binding Motifs: | MA0350.1 akbcwyasCTCATCGcsyywk UP00328A_1 akbcwyasCTCATCGcsyywk M1370_1.02 cgcGATGms M1371_1.02 sscGATGs MA0350.2 asCTCATCGc |
| Binding Sites: | AGCTCATC CCCATCGC CCGATGAC CCGATGAG CCTCATCG CGATGACC CGATGAGA CGATGAGC CGATGCCC CGCGATGA CTCATCAC CTCATCGA CTCATCGC CTCATCTC GATGAGCC GCGATGAC GCGATGCC GGCGATGA TCATCGCA CATCGATG |
| Publications: | *Zhu C, *Byers K, *McCord RP, Shi Z, Berger MF, Newburger D, Saulrieta K, Smith Z, Shah M, Radhakrishnan M, Philippakis AA, Hu Y, De Masi F, Pacek M, Rolfs A , Murthy TVS, LaBaer J, Bulyk ML. High-Resolution DNA Binding Specificity Analysis of Yeast Transcription Factors. Genome Research. Epub January 21, 2009, doi:10.1101/gr.090233.108 (*co-1st authors). [Pubmed] Newburger D.E, Bulyk M.L. UniPROBE: an online database of protein binding microarray data on protein-DNA interactions. Nucleic acids research 37:D77-82 (2009). [Pubmed] |
| Related annotations: | PaperBLAST |
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