Transcription Factor
| Accessions: | Q9UHF7 (JASPAR 2024) |
| Names: | Tricho-rhino-phalangeal syndrome type I protein, TRPS1_HUMAN, Zinc finger protein GC79, Zinc finger transcription factor Trps1 |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q9UHF7 |
| Length: | 1281 |
| Pfam Domains: | 896-929 GATA zinc finger |
| Sequence: (in bold interface residues) | 1 MVRKKNPPLRNVASEGEGQILEPIGTESKVSGKNKEFSADQMSENTDQSDAAELNHKEEH 60 61 SLHVQDPSSSSKKDLKSAVLSEKAGFNYESPSKGGNFPSFPHDEVTDRNMLAFSSPAAGG 120 121 VCEPLKSPQRAEADDPQDMACTPSGDSLETKEDQKMSPKATEETGQAQSGQANCQGLSPV 180 181 SVASKNPQVPSDGGVRLNKSKTDLLVNDNPDPAPLSPELQDFKCNICGYGYYGNDPTDLI 240 241 KHFRKYHLGLHNRTRQDAELDSKILALHNMVQFSHSKDFQKVNRSVFSGVLQDINSSRPV 300 301 LLNGTYDVQVTSGGTFIGIGRKTPDCQGNTKYFRCKFCNFTYMGNSSTELEQHFLQTHPN 360 361 KIKASLPSSEVAKPSEKNSNKSIPALQSSDSGDLGKWQDKITVKAGDDTPVGYSVPIKPL 420 421 DSSRQNGTEATSYYWCKFCSFSCESSSSLKLLEHYGKQHGAVQSGGLNPELNDKLSRGSV 480 481 INQNDLAKSSEGETMTKTDKSSSGAKKKDFSSKGAEDNMVTSYNCQFCDFRYSKSHGPDV 540 541 IVVGPLLRHYQQLHNIHKCTIKHCPFCPRGLCSPEKHLGEITYPFACRKSNCSHCALLLL 600 601 HLSPGAAGSSRVKHQCHQCSFTTPDVDVLLFHYESVHESQASDVKQEANHLQGSDGQQSV 660 661 KESKEHSCTKCDFITQVEEEISRHYRRAHSCYKCRQCSFTAADTQSLLEHFNTVHCQEQD 720 721 ITTANGEEDGHAISTIKEEPKIDFRVYNLLTPDSKMGEPVSESVVKREKLEEKDGLKEKV 780 781 WTESSSDDLRNVTWRGADILRGSPSYTQASLGLLTPVSGTQEQTKTLRDSPNVEAAHLAR 840 841 PIYGLAVETKGFLQGAPAGGEKSGALPQQYPASGENKSKDESQSLLRRRRGSGVFCANCL 900 901 TTKTSLWRKNANGGYVCNACGLYQKLHSTPRPLNIIKQNNGEQIIRRRTRKRLNPEALQA 960 961 EQLNKQQRGSNEEQVNGSPLERRSEDHLTESHQREIPLPSLSKYEAQGSLTKSHSAQQPV 1020 1021 LVSQTLDIHKRMQPLHIQIKSPQESTGDPGNSSSVSEGKGSSERGSPIEKYMRPAKHPNY 1080 1081 SPPGSPIEKYQYPLFGLPFVHNDFQSEADWLRFWSKYKLSVPGNPHYLSHVPGLPNPCQN 1140 1141 YVPYPTFNLPPHFSAVGSDNDIPLDLAIKHSRPGPTANGASKEKTKAPPNVKNEGPLNVV 1200 1201 KTEKVDRSTQDELSTKCVHCGIVFLDEVMYALHMSCHGDSGPFQCSICQHLCTDKYDFTT 1260 1261 HIQRGLHRNNAQVEKNGKPKE |
| Interface Residues: | 677, 679, 680, 683, 703, 706, 707, 905, 906, 908, 918, 922, 923, 926, 948, 1225, 1226, 1228, 1229, 1232, 1253, 1254, 1255, 1256, 1257, 1259, 1260, 1264 |
| 3D-footprint Homologues: | 5yel_A, 3vd6_C, 1gat_A, 3dfx_B, 4gat_A, 7y3l_A, 3uk3_C, 7n5w_A, 8h9h_G, 6ml4_A, 6u9q_A, 5kkq_D, 7y3m_I, 7txc_E, 4x9j_A, 1f2i_J |
| Binding Motifs: | MA1970.1 wwTCTTATCTkw MA1970.2 TCTTATCT |
| Binding Sites: | MA1970.2.13 / MA1970.2.14 / MA1970.2.17 MA1970.2.4 / MA1970.2.6 MA1970.2.16 / MA1970.2.2 MA1970.2.12 MA1970.1.2 / MA1970.1.4 MA1970.1.1 MA1970.1.10 / MA1970.1.14 MA1970.1.11 / MA1970.1.15 MA1970.1.12 / MA1970.1.16 MA1970.1.13 / MA1970.1.17 MA1970.1.14 / MA1970.1.18 MA1970.1.15 MA1970.1.16 / MA1970.1.20 MA1970.1.17 MA1970.1.18 MA1970.1.19 MA1970.1.20 MA1970.1.3 / MA1970.1.5 MA1970.1.4 / MA1970.1.6 MA1970.1.5 / MA1970.1.7 MA1970.1.6 / MA1970.1.8 MA1970.1.7 / MA1970.1.9 MA1970.1.8 MA1970.1.12 / MA1970.1.9 MA1970.2.7 MA1970.2.10 / MA1970.2.11 MA1970.2.19 / MA1970.2.9 MA1970.1.10 MA1970.1.11 MA1970.1.13 MA1970.1.19 MA1970.1.2 MA1970.1.3 MA1970.2.1 MA1970.2.15 MA1970.2.18 MA1970.2.20 / MA1970.2.3 / MA1970.2.5 MA1970.2.8 |
| Publications: | Serandour AA, Mohammed H, Miremadi A, Mulder KW, Carroll JS. TRPS1 regulates oestrogen receptor binding and histone acetylation at enhancers. Oncogene 37:5281-5291 (2018). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.