Transcription Factor

						

			
Accessions: MEF2B_full (HumanTF 1.0)

			
Names: MEF2B, MEF2B neighbor gene protein, MF2NB_HUMAN, Protein MEF2BNB
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Uniprot: Q96FH0
Notes: Ensembl ID: ENSG00000213999; Full protein sequence; TF family: MADS; Clone source: hORFeome
Length: 376
Pfam Domains:     10-59 SRF-type transcription factor (DNA-binding and dimerisation domain)
Sequence: 
(in bold interface residues)		   1 MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSANRLFQYAST   60
  61 DMDRVLLKYTEYSEPHESRTNTDILETLKRRGIGLDGPELEPDEGPEEPGEKFRRLAGEG  120
 121 GDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPP  180
 181 GLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTAT  240
 241 PGPPLGSFPFLPGGPPAPNSCPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQP  300
 301 SGGRSLGEEGPPTRGASPPTPPVSIKSERLSPAPGGPGDFPKTFPYPLLLARSLAEPLRP  360
 361 GPALRRLPLADGWPR*
Interface Residues: 3, 4, 15, 18, 19, 23, 160, 162, 164, 166
3D-footprint Homologues: 1c7u_A, 1hbx_A, 7x1n_C, 1n6j_A, 1mnm_A, 7cuh_A
Binding Motifs: MEF2B_full rCTAwAAATAGm
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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