Transcription Factor

Accessions: UP00396A (UniPROBE 20160601)
Names: "F29F11.5, CEH-22, Homeobox protein ceh-22, Homeobox protein ceh-22"
Organisms: Caenorhabditis elegans
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Description: Homeobox protein ceh-22: C.Elegans Homeobox
Length: 346
Pfam Domains: 190-246 Homeobox domain
Sequence:
(in bold interface residues)
1 MFNVSALAAATPSIASVSSVASPSEQHGLSTSVGVGVNDTTSRTGDGGAASSASSASAAP 60
61 QQQSQSALHNKLEAKWDTLLPTDTNLQCSTWPDSIPLLAGYSATPTFSFDPCTYGSYDPS 120
121 AYFASNGIAGSMYTLPDQFPRSENDMLDNSNTSNGNKSDKDGIKLEDEDEILEDEENDEE 180
181 DDGTGKRKKRKRRVLFTKAQTYELERRFRSQKYLSAPEREALAMQIRLTPTQVKIWFQNH 240
241 RYKTKKSHTDKPINAALLTTMPNAFSSQSTAASFPTRAMPIPMLVRDSSARSSDISSTSP 300
301 YTVAFGSANSGYLPTPSAYLPATSGYFSNGPSAASSYMTNTQWWPS
Interface Residues: 190, 191, 192, 193, 195, 231, 232, 234, 235, 238, 239, 242, 243, 246
3D-footprint Homologues: 3d1n_M, 6a8r_A, 1fjl_B, 2h1k_B, 5zfz_A, 1puf_A, 1ig7_A, 3cmy_A, 1jgg_B, 1nk2_P, 1zq3_P, 3lnq_A, 2lkx_A, 6m3d_C, 1mnm_C, 7q3o_C, 2ld5_A, 6es3_K, 2hdd_A, 1b72_A, 5zjt_E, 4cyc_A, 2r5y_A, 1puf_B, 7psx_B, 2hos_A, 5jlw_D, 4xrs_G, 3a01_E, 1au7_A, 3rkq_B, 5flv_I, 2xsd_C, 1le8_A, 7xrc_C, 8g87_X, 5hod_A, 1du0_A, 4qtr_D, 1k61_B, 1o4x_A
Binding Motifs: UP00396A_1 / UP00396A_2 tsdywrrCCACTTsAmawtwmk
Binding Sites: AAGTACTC
AAGTACTT
ACACTTGA
AGTACTTA
AGTACTTG
ATAAGTGG
CACTTAAG
CACTTCAA
CACTTGAA
CACTTGAC
CACTTGAG
CCACTCGA
CCACTTAA
CCACTTCA
CCACTTGA
GCACTTGA
GGTACTTA
GTACTTAA
GTACTTCA
GTACTTGA
Publications: Berger M.F, Philippakis A.A, Qureshi A.M, He F.S, Estep P.W, Bulyk M.L. Compact, universal DNA microarrays to comprehensively determine transcription-factor binding site specificities. Nature biotechnology 24:1429-35 (2006). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.