Transcription Factor

Accessions: 1hbx_A (3D-footprint 20231221)
Names: SERUM RESPONSE FACTOR, SRF_HUMAN
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P11831
Length: 87
Pfam Domains: 13-63 SRF-type transcription factor (DNA-binding and dimerisation domain)
Sequence:
(in bold interface residues)
1 GKKTRGRVKIKMEFIDNKLRRYTTFSKRKTGIMKKAYELSTLTGTQVLLLVASETGHVYT 60
61 FATRKLQPMITSETGKALIQTCLNSPD
Interface Residues: 4, 7, 8, 19, 22, 23, 27
3D-footprint Homologues: 1hbx_A, 1n6j_A, 1c7u_A, 7x1n_C, 1mnm_A
Binding Motifs: 1hbx_A TTAGGAnnT
1hbx_ABG CGGAAnTCCTAATTAG
Binding Sites: 1hbx_C
1hbx_W
Publications: Hassler M., Richmond T. J. The B-box dominates SAP-1-SRF interactions in the structure of the ternary complex.. EMBO J. 20:3018-3028 (2001). [Pubmed]
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.