Transcription Factor

Accessions: Foxg1_DBD (HumanTF 1.0)
Names: BF-1, BF1, Brain factor 1, Forkhead box protein G1, Forkhead-related protein FKHL1, Foxg1, FOXG1_MOUSE
Organisms: Mus musculus
Libraries: HumanTF 1.0 1
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Uniprot: Q60987
Notes: Ensembl ID: ENSMUSG00000020950; DNA-binding domain sequence; TF family: Forkhead; Clone source: Hughes lab.
Length: 128
Pfam Domains: 18-113 Fork head domain
Sequence:
(in bold interface residues)
1 KDGEGGKEGDKKNGKYEKPPFSYNALIMMAIRQSPEKRLTLNGIYEFIMKNFPYYRENKQ 60
61 GWQNSIRHNLSLNKCFVKVPRHYDDPGKGNYWMLDPSSDDVFIGGTTGKLRRRSTTSRAK 120
121 LAFKRGAR
Interface Residues: 13, 15, 58, 61, 63, 64, 65, 67, 68, 69, 71, 72, 81, 88, 113
3D-footprint Homologues: 7yzb_A, 7yzg_A, 7yz7_A, 3l2c_A, 7vox_H, 2hdc_A, 2c6y_A, 7tdw_A, 3g73_A, 6el8_A, 7tdx_A, 6nce_A, 2uzk_A, 7vou_C, 2a07_J, 7yze_A, 7cby_C, 3co6_C, 6ako_C, 3qrf_G
Binding Motifs: Foxg1_DBD_1 ATAAACAArTGTmAACA
Foxg1_DBD_2 mcGGACACAATC
Foxg1_DBD_3 GTAAACA
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Related annotations: PaperBLAST

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