Transcription Factor

Accessions: 5zjr_A (3D-footprint 20231221)
Names: ABDB_DROME, Homeobox protein abdominal-B, IAB-7, Infraabdominal 7, P3, PH189
Organisms: Drosophila melanogaster
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P09087
Length: 64
Pfam Domains: 4-60 Homeobox domain
Sequence:
(in bold interface residues)
1 EWTRKKRKPYSKFQTLELEKEFLFNAYVSKQKRWELARNLQLTERQVKIWFQNRRMKNKK 60
61 NSQR
Interface Residues: 4, 5, 6, 7, 44, 45, 46, 48, 49, 52, 53, 56, 57, 60
3D-footprint Homologues: 3d1n_M, 1ig7_A, 2h1k_B, 1puf_A, 6a8r_A, 3cmy_A, 1fjl_B, 5zfz_A, 1zq3_P, 2lkx_A, 1nk2_P, 6es3_K, 2ld5_A, 7q3o_C, 3rkq_B, 2r5y_A, 1b72_A, 2hos_A, 7psx_B, 5zjt_E, 4cyc_A, 1jgg_B, 3a01_E, 5jlw_D, 3lnq_A, 1puf_B, 1au7_A, 4xrs_G, 2hdd_A, 6m3d_C, 6cqi_A, 1le8_A, 2xsd_C, 2h8r_B, 1e3o_C, 7xrc_C, 8g87_X, 5flv_I, 1o4x_A, 1le8_B, 6fqp_B, 1du0_A, 5hod_A, 3l1p_A, 4qtr_D, 1mnm_C, 6fqq_E, 1k61_B
Binding Motifs: 5zjr_A TCGTAAA
5zjr_AB TnmTATATCA
Binding Sites: 5zjr_C
5zjr_D
Publications: Zeiske T, Baburajendran N, Kaczynska A, Brasch J, Palmer AG 3rd, Shapiro L, Honig B, Mann RS. Intrinsic DNA Shape Accounts for Affinity Differences between Hox-Cofactor Binding Sites. Cell Rep 24:2221-2230 (2018). [Pubmed]
Related annotations: PaperBLAST

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