Transcription Factor

						

			
Accessions: T049373_1.02 (CISBP 1.02)

			
Names: T049373_1.02;, Zkscan5
Organisms: Mus musculus
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:PBM, family:C2H2 ZF
Length: 492
Pfam Domains:     9-101 SCAN domain
  106-138 KRAB box
  286-307 Zinc-finger double domain
  297-319 C2H2-type zinc finger
  297-319 Zinc finger, C2H2 type
  297-319 C2H2-type zinc finger
  311-334 Zinc-finger double domain
  324-335 C2H2-type zinc finger
  325-347 Zinc finger, C2H2 type
  325-347 C2H2-type zinc finger
  339-363 Zinc-finger double domain
  353-375 C2H2-type zinc finger
  353-375 Zinc finger, C2H2 type
  355-375 C2H2-type zinc finger
  368-390 Zinc-finger double domain
  380-401 C2H2-type zinc finger
  381-403 Zinc finger, C2H2 type
  381-403 C2H2-type zinc finger
  396-419 Zinc-finger double domain
  409-431 C2H2-type zinc finger
  409-431 Zinc finger, C2H2 type
  409-431 C2H2-type zinc finger
  423-446 Zinc-finger double domain
  437-459 Zinc finger, C2H2 type
  437-459 C2H2-type zinc finger
  451-475 Zinc-finger double domain
  465-487 Zinc finger, C2H2 type
  465-487 C2H2-type zinc finger
  465-487 C2H2-type zinc finger
Sequence: 
(in bold interface residues)		   1 MQGYNRPVLETFYQRFKHFQYHEAAGPRDALSQLRVLCCEWLRPELHTKEQILELLVLEQ   60
  61 FLTILPEEFQAWVREHHPESGEEAVAVIESIQRELEERRQQPFIPFIDVAVSFILEEWAH  120
 121 LDQSQKSLGRDSRKEDCESTTPPLKPRVILNRIILMNKIFKKKPPKGRIQNPSPGCVPHT  180
 181 LKAGLPSSAWDAKIKKTGGLAQDDGSRNQGYTEKPCLRPKNNNNNKKKNKKKKKRGHSVG  240
 241 VGSLLPTCGFQGTSSGCLSDHSQGFPGSCISGWPQTPCSQASNFIQHRRIHTGEKPFKCG  300
 301 ECGKSYNQRVHLTQHQRVHTGEKPYKCQVCGKAFRVSSHLVQHHSVHSGERPYGCNECGK  360
 361 SFGRHSHLIEHLKRHFRERPHQCNECGKSFIQSAHLIQHRRIHTGEKPFRCEECGKSYNQ  420
 421 RVHLTQHHRVHTGEKPYACHLCGKAFRVRSHLVQHQSVHSRERPFKCNECGKGFGRRSHL  480
 481 AGHLRLHSRDKS
Interface Residues: 254, 255, 257, 259, 280, 281, 282, 283, 286, 307, 308, 309, 310, 311, 313, 314, 325, 335, 336, 337, 338, 339, 341, 342, 343, 363, 364, 365, 366, 367, 368, 369, 370, 371, 372, 373, 374, 376, 391, 392, 393, 394, 395, 398, 404, 418, 419, 420, 421, 422, 423, 425, 426, 429, 430, 447, 448, 449, 450, 451, 452, 453, 454, 475, 476, 477, 478, 479, 482
3D-footprint Homologues: 8ssq_A, 7w1m_H, 8ssu_A, 5und_A, 2i13_A, 7eyi_G, 1tf3_A, 1mey_C, 5k5i_A, 2gli_A, 5v3j_F, 1llm_D, 2lt7_A, 2kmk_A, 7n5w_A, 2wbs_A, 2drp_D, 8h9h_G, 4m9v_C, 7y3m_I, 5yel_A, 6wmi_A, 5yj3_D, 5k5l_F, 1tf6_A, 6blw_A, 5kkq_D, 6e94_A, 7ysf_A, 2jpa_A, 1ubd_C, 3uk3_C, 6jnm_A, 8cuc_F, 6u9q_A, 5ei9_F, 7txc_E, 5kl3_A, 1f2i_J, 1g2f_F, 6ml4_A, 4x9j_A, 6a57_A, 7y3l_A, 8gn3_A
Binding Motifs: M0435_1.02 mrkardtrAw
			
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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